Myopericytoma in an unusual location.
Dermatol Online J
; 24(4)2018 Apr 15.
Article
in En
| MEDLINE
| ID: mdl-29906007
ABSTRACT
Myopericytoma is a soft-tissue tumor of perivascular cells (pericytes). It is slow-growing, usually asymptomatic, and generally benign, although a malignant variant has been described. The etiology is unknown, but it has been associated with local trauma. The most common location is on the distal extremities. Histologically, it is characterized by a well-circumscribed, non-encapsulated proliferation of spindle shaped cells similar to myofibroblasts with oval nuclei and eosinophilic cytoplasm, arranged in perivascular concentric rings. There are few mitoses and no necrosis is reported. The immunohistochemical analysis is positive for smooth muscle actin and negative or weakly positive for desmin. A low Ki-67 proliferation index is typical. Treatment is surgical excision with free margins. Recurrences after adequate excision are uncommon. We describe a 48-year-old woman with a myopericytoma in an unusual location (next to the inner corner of her left eye) who was treated with surgical excision; there has been no recurrence after 5 years of follow up.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Skin Neoplasms
/
Facial Neoplasms
/
Myofibroma
/
Neoplasm Recurrence, Local
Limits:
Female
/
Humans
/
Middle aged
Language:
En
Journal:
Dermatol Online J
Journal subject:
DERMATOLOGIA
Year:
2018
Document type:
Article