Neuritin promotes neurite and spine growth in rat cerebellar granule cells via L-type calcium channel-mediated calcium influx.

Zhao, Qian-Ru; Lu, Jun-Mei; Li, Zhao-Yang; Mei, Yan-Ai

Zhao, Qian-Ru; Lu, Jun-Mei; Li, Zhao-Yang; Mei, Yan-Ai.

Affiliation

Zhao QR; Institutes of Brain Science, State Key Laboratory of Medical Neurobiology and School of Life Sciences, Fudan University, Shanghai, China.
Lu JM; Institutes of Brain Science, State Key Laboratory of Medical Neurobiology and School of Life Sciences, Fudan University, Shanghai, China.
Li ZY; Institutes of Brain Science, State Key Laboratory of Medical Neurobiology and School of Life Sciences, Fudan University, Shanghai, China.
Mei YA; Institutes of Brain Science, State Key Laboratory of Medical Neurobiology and School of Life Sciences, Fudan University, Shanghai, China.

J Neurochem ; 147(1): 40-57, 2018 10.

Article in En | MEDLINE | ID: mdl-29920676

Subject(s)

Calcium Channels, L-Type/drug effects; Calcium Signaling/drug effects; Cerebellum/cytology; Dendritic Spines/drug effects; Neurites/drug effects; Neuropeptides/pharmacology; Animals; Calcium Channels/metabolism; Calcium Channels, L-Type/metabolism; Cerebellum/drug effects; Cerebellum/growth & development; Cytoplasmic Granules/drug effects; Female; GPI-Linked Proteins/pharmacology; Gene Silencing; Humans; Insulin/pharmacology; MAP Kinase Signaling System/drug effects; NFATC Transcription Factors/antagonists & inhibitors; NFATC Transcription Factors/genetics; Rats; Rats, Sprague-Dawley; Receptor, Insulin/antagonists & inhibitors

Key words

Ca2+-CaN-NFATc4 axis; L-type calcium channel; cerebellar granule neurons; insulin receptor; neurite and spine growth; neuritin

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Neuropeptides / Cerebellum / Neurites / Calcium Signaling / Calcium Channels, L-Type / Dendritic Spines Limits: Animals / Female / Humans Language: En Journal: J Neurochem Year: 2018 Document type: Article Affiliation country: China Country of publication: United kingdom

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