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Identification and characterisation of carnostatine (SAN9812), a potent and selective carnosinase (CN1) inhibitor with in vivo activity.
Qiu, Jiedong; Hauske, Sibylle J; Zhang, Shiqi; Rodriguez-Niño, Angelica; Albrecht, Thomas; Pastene, Diego O; van den Born, Jacob; van Goor, Harry; Ruf, Sven; Kohlmann, Markus; Teufel, Michael; Krämer, Bernhard K; Hammes, Hans-Peter; Peters, Verena; Yard, Benito A; Kannt, Aimo.
Affiliation
  • Qiu J; 5th Medical Department, Universitätsklinikum Mannheim, Mannheim, Germany.
  • Hauske SJ; 5th Medical Department, Universitätsklinikum Mannheim, Mannheim, Germany.
  • Zhang S; 5th Medical Department, Universitätsklinikum Mannheim, Mannheim, Germany.
  • Rodriguez-Niño A; 5th Medical Department, Universitätsklinikum Mannheim, Mannheim, Germany.
  • Albrecht T; 5th Medical Department, Universitätsklinikum Mannheim, Mannheim, Germany.
  • Pastene DO; 5th Medical Department, Universitätsklinikum Mannheim, Mannheim, Germany.
  • van den Born J; Department of Nephrology, University Medical Centre Groningen, Groningen, Netherlands.
  • van Goor H; Department of Pathology and Medical Biology, University Medical Centre Groningen, Groningen, Netherlands.
  • Ruf S; Sanofi Research and Development, Frankfurt am Main, Germany.
  • Kohlmann M; Sanofi Research and Development, Frankfurt am Main, Germany.
  • Teufel M; Sanofi Research and Development, Frankfurt am Main, Germany.
  • Krämer BK; Translational Medicine Oncology, Bayer Healthcare Pharmaceuticals, Whippany, NJ, USA.
  • Hammes HP; 5th Medical Department, Universitätsklinikum Mannheim, Mannheim, Germany.
  • Peters V; European Center for Angioscience, Mannheim, Germany.
  • Yard BA; 5th Medical Department, Universitätsklinikum Mannheim, Mannheim, Germany.
  • Kannt A; European Center for Angioscience, Mannheim, Germany.
Amino Acids ; 51(1): 7-16, 2019 Jan.
Article in En | MEDLINE | ID: mdl-29922921
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Propionates / Protease Inhibitors / Carnosine / Dipeptidases / Small Molecule Libraries / Drug Discovery / Imidazoles Type of study: Diagnostic_studies / Prognostic_studies Limits: Adult / Animals / Female / Humans / Male Language: En Journal: Amino Acids Journal subject: BIOQUIMICA Year: 2019 Document type: Article Affiliation country: Germany Country of publication: Austria
Fulltext
Add to My VHL
Print
XML
PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Propionates / Protease Inhibitors / Carnosine / Dipeptidases / Small Molecule Libraries / Drug Discovery / Imidazoles Type of study: Diagnostic_studies / Prognostic_studies Limits: Adult / Animals / Female / Humans / Male Language: En Journal: Amino Acids Journal subject: BIOQUIMICA Year: 2019 Document type: Article Affiliation country: Germany Country of publication: Austria