Early urinary candidate biomarker discovery in a rat thioacetamide-induced liver fibrosis model.

Zhang, Fanshuang; Ni, Yanying; Yuan, Yuan; Yin, Wei; Gao, Youhe

Zhang, Fanshuang; Ni, Yanying; Yuan, Yuan; Yin, Wei; Gao, Youhe.

Affiliation

Zhang F; Department of Pathology, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.
Ni Y; Department of Pathophysiology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Beijing, 10005, China.
Yuan Y; Department of Pathophysiology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Beijing, 10005, China.
Yin W; Department of Pathophysiology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Beijing, 10005, China.
Gao Y; Department of Pathology, Beijing Tiantan Hospital, Capital Medical University, Beijing, 100050, China.

Sci China Life Sci ; 61(11): 1369-1381, 2018 Nov.

Article in En | MEDLINE | ID: mdl-29961236

Subject(s)

Biomarkers/urine; Disease Models, Animal; Liver Cirrhosis/chemically induced; Liver Cirrhosis/urine; Thioacetamide/toxicity; Animals; Liver Cirrhosis/blood; Liver Cirrhosis/pathology; Male; Mass Spectrometry; Proteomics; Rats; Rats, Sprague-Dawley; Reproducibility of Results

Key words

animal model; biomarker; liver fibrosis; proteomics; urine

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thioacetamide / Biomarkers / Disease Models, Animal / Liver Cirrhosis Type of study: Prognostic_studies Limits: Animals Language: En Journal: Sci China Life Sci Journal subject: BIOLOGIA / CIENCIA Year: 2018 Document type: Article Affiliation country: China Country of publication: China

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