PTP&#945; is required for laminin-2-induced Fyn-Akt signaling to drive oligodendrocyte differentiation.

Ly, Philip T T; Stewart, Craig; Pallen, Catherine J

PTPα is required for laminin-2-induced Fyn-Akt signaling to drive oligodendrocyte differentiation.

Ly, Philip T T; Stewart, Craig; Pallen, Catherine J.

Affiliation

Ly PTT; Department of Pediatrics, University of British Columbia, Vancouver, British Columbia V5Z 4H4, Canada.
Stewart C; BC Children's Hospital Research Institute, University of British Columbia, Vancouver, British Columbia V5Z 4H4, Canada.
Pallen CJ; International Collaboration on Repair Discoveries, University of British Columbia, Vancouver, British Columbia V5Z 4H4, Canada.

J Cell Sci ; 131(15)2018 08 06.

Article in En | MEDLINE | ID: mdl-29991512

Subject(s)

Laminin/metabolism; Oligodendroglia/cytology; Oligodendroglia/metabolism; Proto-Oncogene Proteins c-akt/metabolism; Proto-Oncogene Proteins c-fyn/metabolism; Receptor-Like Protein Tyrosine Phosphatases, Class 4/metabolism; Animals; Cell Differentiation/genetics; Cell Differentiation/physiology; Cells, Cultured; Female; Immunoblotting; Immunohistochemistry; Immunoprecipitation; Male; Mice; Mice, Inbred C57BL; Proto-Oncogene Proteins c-akt/genetics; Proto-Oncogene Proteins c-fyn/genetics; Receptor-Like Protein Tyrosine Phosphatases, Class 4/genetics; Signal Transduction/genetics; Signal Transduction/physiology

Key words

Akt; Fyn; Laminin; Oligodendrocyte; PTPRA; PTPα; Protein tyrosine phosphatase alpha

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oligodendroglia / Laminin / Proto-Oncogene Proteins c-akt / Proto-Oncogene Proteins c-fyn / Receptor-Like Protein Tyrosine Phosphatases, Class 4 Type of study: Prognostic_studies Limits: Animals Language: En Journal: J Cell Sci Year: 2018 Document type: Article Affiliation country: Canada

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