Hydrodynamics of Diffusion in Lipid Membrane Simulations.
Phys Rev Lett
; 120(26): 268104, 2018 Jun 29.
Article
in En
| MEDLINE
| ID: mdl-30004782
ABSTRACT
By performing molecular dynamics simulations with up to 132 million coarse-grained particles in half-micron sized boxes, we show that hydrodynamics quantitatively explains the finite-size effects on diffusion of lipids, proteins, and carbon nanotubes in membranes. The resulting Oseen correction allows us to extract infinite-system diffusion coefficients and membrane surface viscosities from membrane simulations despite the logarithmic divergence of apparent diffusivities with increasing box width. The hydrodynamic theory of diffusion applies also to membranes with asymmetric leaflets and embedded proteins, and to a complex plasma-membrane mimetic.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Cell Membrane
/
Membrane Lipids
/
Models, Chemical
Language:
En
Journal:
Phys Rev Lett
Year:
2018
Document type:
Article
Affiliation country:
Germany