A-type K<sup>+</sup> channels impede supralinear summation of clustered glutamatergic inputs in layer 3 neocortical pyramidal neurons.

Biró, Ágota A; Brémaud, Antoine; Falck, Joanne; Ruiz, Arnaud J

A-type K⁺ channels impede supralinear summation of clustered glutamatergic inputs in layer 3 neocortical pyramidal neurons.

Biró, Ágota A; Brémaud, Antoine; Falck, Joanne; Ruiz, Arnaud J.

Affiliation

Biró ÁA; UCL School of Pharmacy, Brunswick Square, London WC1N 1AX, United Kingdom.
Brémaud A; UCL School of Pharmacy, Brunswick Square, London WC1N 1AX, United Kingdom.
Falck J; UCL School of Pharmacy, Brunswick Square, London WC1N 1AX, United Kingdom.
Ruiz AJ; UCL School of Pharmacy, Brunswick Square, London WC1N 1AX, United Kingdom. Electronic address: a.ruiz@ucl.ac.uk.

Neuropharmacology ; 140: 86-99, 2018 09 15.

Article in En | MEDLINE | ID: mdl-30009837

Subject(s)

Glutamic Acid/physiology; Neocortex/cytology; Pyramidal Cells/physiology; Shal Potassium Channels/physiology; 4-Aminopyridine/pharmacology; Action Potentials/physiology; Animals; Dendrites/physiology; Dendritic Spines/physiology; Excitatory Postsynaptic Potentials/physiology; Female; Glutamic Acid/analogs & derivatives; Glutamic Acid/pharmacology; Male; Mice; Models, Neurological; Neocortex/physiology; Organometallic Compounds/pharmacology; Shal Potassium Channels/antagonists & inhibitors; Spider Venoms/pharmacology

Key words

4-Aminopyridine; I(A); Mice; Neocortex; Phrixotoxin-2; RuBi-glutamate

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyramidal Cells / Glutamic Acid / Neocortex / Shal Potassium Channels Type of study: Prognostic_studies Limits: Animals Language: En Journal: Neuropharmacology Year: 2018 Document type: Article Affiliation country: United kingdom Country of publication: United kingdom

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