Tumor thrombus in the large veins draining primary pelvic osteosarcoma on cross sectional imaging.
Eur J Radiol
; 105: 49-55, 2018 Aug.
Article
in En
| MEDLINE
| ID: mdl-30017298
ABSTRACT
PURPOSE:
To evaluate the frequency of tumor thrombus in the large veins draining primary pelvic osteosarcoma on early cross-sectional imaging studies and its effect on patient survival. MATERIALS ANDMETHODS:
Our retrospective study included all patients with primary pelvic osteosarcoma treated at our facility between January 2000 and May 2014, who were ≤ 45 years of age, and had adequate imaging studies and clinical follow up. Four radiologists evaluated for tumor in the large draining veins on initial CT, MRI and PET/CTs. A consensus evaluation by the four radiologists together with findings on operative reports, pathology reports or follow-up imaging was used as the reference standard.RESULTS:
Thirty-nine patients with primary pelvic osteosarcoma met final inclusion criteria. Tumor thrombus was identified in the large draining veins in 10 of the 22 (45%) patients who underwent tumor resection and 10 of the 17 (59%) who did not. In the 22 patients who underwent tumor resection, tumor thrombus was significantly associated with worse overall survival (pâ¯=â¯0.03).CONCLUSIONS:
Tumor thrombus in the large draining veins is identified in a significant proportion of initial imaging studies in patients with pelvic osteosarcoma, and is associated with worse overall survival in patients who undergo tumor resection.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Pelvic Bones
/
Thrombophlebitis
/
Bone Neoplasms
/
Osteosarcoma
Type of study:
Observational_studies
/
Prevalence_studies
/
Prognostic_studies
/
Risk_factors_studies
Limits:
Adolescent
/
Adult
/
Child
/
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Eur J Radiol
Year:
2018
Document type:
Article