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Shutdown of ER-associated degradation pathway rescues functions of mutant iduronate 2-sulfatase linked to mucopolysaccharidosis type II.
Osaki, Yosuke; Saito, Atsushi; Kanemoto, Soshi; Kaneko, Masayuki; Matsuhisa, Koji; Asada, Rie; Masaki, Takao; Orii, Kenji; Fukao, Toshiyuki; Tomatsu, Shunji; Imaizumi, Kazunori.
Affiliation
  • Osaki Y; Department of Biochemistry, Institute of Biomedical & Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8553, Japan.
  • Saito A; Department of Stress Protein Processing, Institute of Biomedical & Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8553, Japan.
  • Kanemoto S; Department of Nephrology, Hiroshima University Hospital, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8553, Japan.
  • Kaneko M; Department of Stress Protein Processing, Institute of Biomedical & Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8553, Japan. saitoa@hiroshima-u.ac.jp.
  • Matsuhisa K; Department of Biochemistry, Institute of Biomedical & Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8553, Japan.
  • Asada R; Department of Biochemistry, Institute of Biomedical & Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8553, Japan.
  • Masaki T; Department of Stress Protein Processing, Institute of Biomedical & Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8553, Japan.
  • Orii K; Department of Biochemistry, Institute of Biomedical & Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8553, Japan.
  • Fukao T; Department of Nephrology, Hiroshima University Hospital, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8553, Japan.
  • Tomatsu S; Department of Pediatrics, Graduate School of Medicine, Gifu University, 1-1 Yanagido, Gifu, 501-1193, Japan.
  • Imaizumi K; Department of Pediatrics, Graduate School of Medicine, Gifu University, 1-1 Yanagido, Gifu, 501-1193, Japan.
Cell Death Dis ; 9(8): 808, 2018 07 24.
Article in En | MEDLINE | ID: mdl-30042467
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Glycoproteins / Endoplasmic Reticulum / Endoplasmic Reticulum-Associated Degradation Type of study: Risk_factors_studies Limits: Humans Language: En Journal: Cell Death Dis Year: 2018 Document type: Article Affiliation country: Japan Country of publication: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Glycoproteins / Endoplasmic Reticulum / Endoplasmic Reticulum-Associated Degradation Type of study: Risk_factors_studies Limits: Humans Language: En Journal: Cell Death Dis Year: 2018 Document type: Article Affiliation country: Japan Country of publication: United kingdom