Effect of irradiation and bone marrow transplantation on angiotensin II-induced aortic inflammation in ApoE knockout mice.

Patel, Jyoti; Douglas, Gillian; Kerr, Alastair G; Hale, Ashley B; Channon, Keith M

Patel, Jyoti; Douglas, Gillian; Kerr, Alastair G; Hale, Ashley B; Channon, Keith M.

Affiliation

Patel J; Division of Cardiovascular Medicine, British Heart Foundation Centre of Research Excellence, Radcliffe Department of Medicine, John Radcliffe Hospital, University of Oxford, Oxford, OX3 9DU, UK; Wellcome Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK. Electronic address: jyoti.
Douglas G; Division of Cardiovascular Medicine, British Heart Foundation Centre of Research Excellence, Radcliffe Department of Medicine, John Radcliffe Hospital, University of Oxford, Oxford, OX3 9DU, UK; Wellcome Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK.
Kerr AG; Department of Physiology, Anatomy, and Genetics, University of Oxford, Oxford, OX1 3QX, UK.
Hale AB; Division of Cardiovascular Medicine, British Heart Foundation Centre of Research Excellence, Radcliffe Department of Medicine, John Radcliffe Hospital, University of Oxford, Oxford, OX3 9DU, UK; Wellcome Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK.
Channon KM; Division of Cardiovascular Medicine, British Heart Foundation Centre of Research Excellence, Radcliffe Department of Medicine, John Radcliffe Hospital, University of Oxford, Oxford, OX3 9DU, UK; Wellcome Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK.

Atherosclerosis ; 276: 74-82, 2018 09.

Article in En | MEDLINE | ID: mdl-30048944

Subject(s)

Angiotensin II; Aortic Aneurysm, Abdominal/prevention & control; Aortic Aneurysm, Thoracic/prevention & control; Aortitis/prevention & control; Atherosclerosis/prevention & control; Bone Marrow Transplantation; Whole-Body Irradiation; Animals; Aorta, Abdominal/metabolism; Aorta, Abdominal/pathology; Aorta, Thoracic/metabolism; Aorta, Thoracic/pathology; Aortic Aneurysm, Abdominal/chemically induced; Aortic Aneurysm, Abdominal/genetics; Aortic Aneurysm, Abdominal/metabolism; Aortic Aneurysm, Thoracic/chemically induced; Aortic Aneurysm, Thoracic/genetics; Aortic Aneurysm, Thoracic/metabolism; Aortic Rupture/chemically induced; Aortic Rupture/genetics; Aortic Rupture/metabolism; Aortic Rupture/prevention & control; Aortitis/chemically induced; Aortitis/genetics; Aortitis/metabolism; Atherosclerosis/chemically induced; Atherosclerosis/genetics; Atherosclerosis/metabolism; Disease Models, Animal; Macrophages/metabolism; Macrophages/radiation effects; Macrophages/transplantation; Male; Mice, Knockout, ApoE; Monocytes/metabolism; Monocytes/radiation effects; Monocytes/transplantation; Plaque, Atherosclerotic

Key words

Aneurysm; Angiotensin II; Bone marrow transplantation; Monocyte

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Aortitis / Angiotensin II / Whole-Body Irradiation / Bone Marrow Transplantation / Aortic Aneurysm, Thoracic / Aortic Aneurysm, Abdominal / Atherosclerosis Language: En Journal: Atherosclerosis Year: 2018 Document type: Article

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