Overexpression of FGFR3 in HPV-positive Tonsillar and Base of Tongue Cancer Is Correlated to Outcome.

Bersani, Cinzia; Haeggblom, Linnea; Ursu, Ramona G; Giusca, Simona E; Marklund, Linda; Ramqvist, Torbjörn; Näsman, Anders; Dalianis, Tina

Bersani, Cinzia; Haeggblom, Linnea; Ursu, Ramona G; Giusca, Simona E; Marklund, Linda; Ramqvist, Torbjörn; Näsman, Anders; Dalianis, Tina.

Affiliation

Bersani C; Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
Haeggblom L; Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
Ursu RG; Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
Giusca SE; University of Medicine and Pharmacy Grigore T. Popa, Iasi, Romania.
Marklund L; University of Medicine and Pharmacy Grigore T. Popa, Iasi, Romania.
Ramqvist T; CLINTEC, Karolinska Institutet, Stockholm, Sweden.
Näsman A; Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
Dalianis T; Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.

Anticancer Res ; 38(8): 4683-4690, 2018 Aug.

Article in En | MEDLINE | ID: mdl-30061236

Subject(s)

Papillomavirus Infections/genetics; Receptor, Fibroblast Growth Factor, Type 3/genetics; Tongue Neoplasms/genetics; Tongue Neoplasms/pathology; Tonsillar Neoplasms/genetics; Tonsillar Neoplasms/pathology; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor/genetics; Carcinoma, Squamous Cell/genetics; Carcinoma, Squamous Cell/pathology; Carcinoma, Squamous Cell/virology; Disease-Free Survival; Female; Head and Neck Neoplasms/genetics; Head and Neck Neoplasms/pathology; Head and Neck Neoplasms/virology; Humans; Immunohistochemistry; Male; Middle Aged; Mutation/genetics; Papillomaviridae/pathogenicity; Papillomavirus Infections/pathology; Prognosis; Squamous Cell Carcinoma of Head and Neck; Tongue Neoplasms/virology; Tonsillar Neoplasms/virology

Key words

FGFR3; FGFR3 immunohistochemistry; HPV; base of tongue cancer; oropharyngeal cancer; survival; tonsillar cancer

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tongue Neoplasms / Tonsillar Neoplasms / Papillomavirus Infections / Receptor, Fibroblast Growth Factor, Type 3 Type of study: Prognostic_studies Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Anticancer Res Year: 2018 Document type: Article Affiliation country: Sweden Country of publication: Greece

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