Acute intestinal ischaemia from a portal vein thrombosis in a young female smoker on an oral contraceptive.
BMJ Case Rep
; 20182018 Aug 04.
Article
in En
| MEDLINE
| ID: mdl-30077981
ABSTRACT
We report the case of a 23-year-old woman who presented with bloody diarrhoea and multiple syncopal events. While the initial diagnosis clinically appeared to be inflammatory bowel disease, she was found to have a portal vein thrombosis (PVT) on MR cholangiopancreatography and acute intestinal ischaemia on colonic biopsy. The aetiology of this patient's PVT is attributed to her acquired prothrombotic state from an estrogen-containing contraceptive pill in conjunction with regular tobacco use. Extensive mesenteric venous thrombosis from an acute PVT has been shown to cause intestinal ischaemia, likely from venous obstruction and reflexive arterial constriction; however, the diagnosis is often delayed until surgery or autopsy. Our case report highlights this patient's clinical presentation, workup and treatment, as part of a review for the risk factors and guidelines recommendations for management of an acute PVT.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Portal Vein
/
Smoking
/
Contraceptives, Oral, Hormonal
/
Mesenteric Ischemia
Type of study:
Diagnostic_studies
/
Etiology_studies
/
Guideline
/
Risk_factors_studies
Limits:
Adult
/
Female
/
Humans
Language:
En
Journal:
BMJ Case Rep
Year:
2018
Document type:
Article
Affiliation country:
United States