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Aryl hydrocarbon receptor activation by benzo(a)pyrene inhibits proliferation of myeloid precursor cells and alters the differentiation state as well as the functional phenotype of murine bone marrow-derived macrophages.
Riemschneider, Sina; Kohlschmidt, Janine; Fueldner, Christiane; Esser, Charlotte; Hauschildt, Sunna; Lehmann, Jörg.
Affiliation
  • Riemschneider S; Department of Therapy Validation, Fraunhofer Institute for Cell Therapy and Immunology, 04103, Leipzig, Germany. Electronic address: sina.riemschneider@izi.fraunhofer.de.
  • Kohlschmidt J; Department of Therapy Validation, Fraunhofer Institute for Cell Therapy and Immunology, 04103, Leipzig, Germany. Electronic address: janine.kohlschmidt@izi.fraunhofer.de.
  • Fueldner C; Department of Therapy Validation, Fraunhofer Institute for Cell Therapy and Immunology, 04103, Leipzig, Germany. Electronic address: christiane.fueldner@zv.uni-leipzig.de.
  • Esser C; Leibniz Research Institute for Environmental Medicine, 40225, Düsseldorf, Germany. Electronic address: charlotte.esser@uni-duesseldorf.de.
  • Hauschildt S; Department of Immunobiology, Faculty of Life Sciences, University of Leipzig, 04103, Leipzig, Germany. Electronic address: shaus@rz.uni-leipzig.de.
  • Lehmann J; Department of Therapy Validation, Fraunhofer Institute for Cell Therapy and Immunology, 04103, Leipzig, Germany. Electronic address: joerg.lehmann@izi.fraunhofer.de.
Toxicol Lett ; 296: 106-113, 2018 Oct 15.
Article in En | MEDLINE | ID: mdl-30099064
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Benzo(a)pyrene / Bone Marrow Cells / Cell Differentiation / Receptors, Aryl Hydrocarbon / Myeloid Progenitor Cells / Cell Proliferation / Macrophages Limits: Animals Language: En Journal: Toxicol Lett Year: 2018 Document type: Article Country of publication: Netherlands
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Benzo(a)pyrene / Bone Marrow Cells / Cell Differentiation / Receptors, Aryl Hydrocarbon / Myeloid Progenitor Cells / Cell Proliferation / Macrophages Limits: Animals Language: En Journal: Toxicol Lett Year: 2018 Document type: Article Country of publication: Netherlands