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Efficiently controlling for case-control imbalance and sample relatedness in large-scale genetic association studies.
Zhou, Wei; Nielsen, Jonas B; Fritsche, Lars G; Dey, Rounak; Gabrielsen, Maiken E; Wolford, Brooke N; LeFaive, Jonathon; VandeHaar, Peter; Gagliano, Sarah A; Gifford, Aliya; Bastarache, Lisa A; Wei, Wei-Qi; Denny, Joshua C; Lin, Maoxuan; Hveem, Kristian; Kang, Hyun Min; Abecasis, Goncalo R; Willer, Cristen J; Lee, Seunggeun.
Affiliation
  • Zhou W; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.
  • Nielsen JB; Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, USA.
  • Fritsche LG; Department of Internal Medicine, Division of Cardiology, University of Michigan Medical School, Ann Arbor, MI, USA.
  • Dey R; Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, USA.
  • Gabrielsen ME; K. G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Norwegian University of Science and Technology, Trondheim, Norway.
  • Wolford BN; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA.
  • LeFaive J; Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, USA.
  • VandeHaar P; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA.
  • Gagliano SA; K. G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Norwegian University of Science and Technology, Trondheim, Norway.
  • Gifford A; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.
  • Bastarache LA; Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, USA.
  • Wei WQ; Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, USA.
  • Denny JC; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA.
  • Lin M; Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, USA.
  • Hveem K; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA.
  • Kang HM; Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, USA.
  • Abecasis GR; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA.
  • Willer CJ; Department of Biomedical Informatics, Vanderbilt University, Nashville, TN, USA.
  • Lee S; Department of Biomedical Informatics, Vanderbilt University, Nashville, TN, USA.
Nat Genet ; 50(9): 1335-1341, 2018 09.
Article in En | MEDLINE | ID: mdl-30104761
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Genome-Wide Association Study Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: Nat Genet Journal subject: GENETICA MEDICA Year: 2018 Document type: Article Affiliation country: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Genome-Wide Association Study Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: Nat Genet Journal subject: GENETICA MEDICA Year: 2018 Document type: Article Affiliation country: United States