Immune checkpoints and cancer in the immunogenomics era.

Park, Ryan; Winnicki, Mary; Liu, Evan; Chu, Wen-Ming

Park, Ryan; Winnicki, Mary; Liu, Evan; Chu, Wen-Ming.

Affiliation

Park R; University of Hawaii Cancer Center. He is an expert in the innate immunity and chronic inflammation-associated cancer fields.
Winnicki M; University of Hawaii Cancer Center and studies the mechanisms of chronic inflammation-associated cancer.
Liu E; University of Hawaii Cancer Center and studies the mechanisms of chronic inflammation-associated cancer.
Chu WM; University of Hawaii Cancer Center and studies the mechanisms of chronic inflammation-associated cancer.

Brief Funct Genomics ; 18(2): 133-139, 2019 03 22.

Article in En | MEDLINE | ID: mdl-30137232

Subject(s)

Antineoplastic Agents, Immunological/therapeutic use; Genomics/methods; Immunotherapy/methods; Neoplasm Proteins/antagonists & inhibitors; Neoplasms/drug therapy; Animals; Humans; Neoplasm Proteins/genetics; Neoplasms/genetics; Neoplasms/immunology

Key words

POLE; CTLA-4; MMR deficiency; PD-1; PD-L1; immune checkpoint blockade; immunogenomics; mutation; neoantigen; resistance to checkpoint blockade; somatic

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Genomics / Antineoplastic Agents, Immunological / Immunotherapy / Neoplasm Proteins / Neoplasms Limits: Animals / Humans Language: En Journal: Brief Funct Genomics Year: 2019 Document type: Article Country of publication: United kingdom

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