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Optimizing the radiosynthesis of [68Ga]DOTA-MLN6907 peptide containing three disulfide cyclization bonds - a GCC specific chelate for clinical radiopharmaceuticals.
Ghai, Anchal; Singh, Baljinder; Li, Mengshi; Daniels, Tamara A; Coelho, Richard; Orcutt, Kelly; Watkins, G Leonard; Norenberg, Jeffrey P; Cvet, Donna; Schultz, Michael K.
Affiliation
  • Ghai A; Department of Nuclear Medicine, Postgraduate Institute of Medical Education & Research, Sector 12, Chandigarh 160012, India.
  • Singh B; Department of Nuclear Medicine, Postgraduate Institute of Medical Education & Research, Sector 12, Chandigarh 160012, India.
  • Li M; Department of Radiology, The University of Iowa, 200 Hawkins Drive, Iowa City, IA 52242, USA; Departments of Radiation Oncology (Free Radical and Radiation Biology Program), Pediatrics, and Chemistry, and the Interdisciplinary Program in Human Toxicology, The University of Iowa, 500 N Road, ML B180,
  • Daniels TA; Radiopharmaceutical Sciences, University of New Mexico Health Sciences Center, Albuquerque, NM 87131, USA.
  • Coelho R; InviCRO, LLC, 27 Drydock Avenue, Boston, MA 02210 , USA.
  • Orcutt K; InviCRO, LLC, 27 Drydock Avenue, Boston, MA 02210 , USA.
  • Watkins GL; Department of Radiology, The University of Iowa, 200 Hawkins Drive, Iowa City, IA 52242, USA.
  • Norenberg JP; Radiopharmaceutical Sciences, University of New Mexico Health Sciences Center, Albuquerque, NM 87131, USA.
  • Cvet D; Takeda Pharmaceuticals, 40 Landsdowne Street, Cambridge, MA 02139, USA.
  • Schultz MK; Department of Radiology, The University of Iowa, 200 Hawkins Drive, Iowa City, IA 52242, USA; Departments of Radiation Oncology (Free Radical and Radiation Biology Program), Pediatrics, and Chemistry, and the Interdisciplinary Program in Human Toxicology, The University of Iowa, 500 N Road, ML B180,
Appl Radiat Isot ; 140: 333-341, 2018 Oct.
Article in En | MEDLINE | ID: mdl-30138815
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptides / Radiopharmaceuticals / Gallium Radioisotopes / Heterocyclic Compounds, 1-Ring Limits: Humans Language: En Journal: Appl Radiat Isot Journal subject: MEDICINA NUCLEAR / SAUDE AMBIENTAL Year: 2018 Document type: Article Affiliation country: India Country of publication: United kingdom
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptides / Radiopharmaceuticals / Gallium Radioisotopes / Heterocyclic Compounds, 1-Ring Limits: Humans Language: En Journal: Appl Radiat Isot Journal subject: MEDICINA NUCLEAR / SAUDE AMBIENTAL Year: 2018 Document type: Article Affiliation country: India Country of publication: United kingdom