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Strategies for controlling CRISPR/Cas9 off-target effects and biological variations in mammalian genome editing experiments.
Kimberland, Michelle L; Hou, Wangfang; Alfonso-Pecchio, Adolfo; Wilson, Stephen; Rao, Yanhua; Zhang, Shu; Lu, Quinn.
Affiliation
  • Kimberland ML; Target Sciences, GlaxoSmithKline R&D, 1250 South Collegeville Road, Collegeville, PA 19426, USA.
  • Hou W; Target Sciences, GlaxoSmithKline R&D, 1250 South Collegeville Road, Collegeville, PA 19426, USA.
  • Alfonso-Pecchio A; Target Sciences, GlaxoSmithKline R&D, 1250 South Collegeville Road, Collegeville, PA 19426, USA.
  • Wilson S; Platform Technology & Science, GlaxoSmithKline R&D, Gunnels Wood Road, Stevenage, SG1 2NY, UK.
  • Rao Y; Target Sciences, GlaxoSmithKline R&D, 1250 South Collegeville Road, Collegeville, PA 19426, USA.
  • Zhang S; Target Sciences, GlaxoSmithKline R&D, 1250 South Collegeville Road, Collegeville, PA 19426, USA.
  • Lu Q; Target Sciences, GlaxoSmithKline R&D, 1250 South Collegeville Road, Collegeville, PA 19426, USA. Electronic address: Quinn.2.Lu@GSK.com.
J Biotechnol ; 284: 91-101, 2018 Oct 20.
Article in En | MEDLINE | ID: mdl-30142414
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: CRISPR-Cas Systems / Gene Editing Limits: Animals / Humans Language: En Journal: J Biotechnol Journal subject: BIOTECNOLOGIA Year: 2018 Document type: Article Affiliation country: United States Country of publication: Netherlands
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: CRISPR-Cas Systems / Gene Editing Limits: Animals / Humans Language: En Journal: J Biotechnol Journal subject: BIOTECNOLOGIA Year: 2018 Document type: Article Affiliation country: United States Country of publication: Netherlands