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The NORAD lncRNA assembles a topoisomerase complex critical for genome stability.
Munschauer, Mathias; Nguyen, Celina T; Sirokman, Klara; Hartigan, Christina R; Hogstrom, Larson; Engreitz, Jesse M; Ulirsch, Jacob C; Fulco, Charles P; Subramanian, Vidya; Chen, Jenny; Schenone, Monica; Guttman, Mitchell; Carr, Steven A; Lander, Eric S.
Affiliation
  • Munschauer M; Broad Institute of MIT and Harvard, Cambridge, MA, USA. mathias@broadinstitute.org.
  • Nguyen CT; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Sirokman K; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Hartigan CR; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Hogstrom L; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Engreitz JM; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Ulirsch JC; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Fulco CP; Division of Hematology/Oncology, Boston Children's Hospital and Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Subramanian V; Program in Biological and Biomedical Sciences, Harvard University, Cambridge, MA, USA.
  • Chen J; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Schenone M; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Guttman M; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Carr SA; Division of Health Sciences and Technology, MIT, Cambridge, MA, USA.
  • Lander ES; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Nature ; 561(7721): 132-136, 2018 09.
Article in En | MEDLINE | ID: mdl-30150775

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: RNA-Binding Proteins / DNA Topoisomerases, Type I / Genomic Instability / Multiprotein Complexes / RNA, Long Noncoding Type of study: Prognostic_studies Limits: Humans Language: En Journal: Nature Year: 2018 Document type: Article Affiliation country: United States Country of publication: United kingdom

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: RNA-Binding Proteins / DNA Topoisomerases, Type I / Genomic Instability / Multiprotein Complexes / RNA, Long Noncoding Type of study: Prognostic_studies Limits: Humans Language: En Journal: Nature Year: 2018 Document type: Article Affiliation country: United States Country of publication: United kingdom