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Ursodeoxycholic Acid Improves Mitochondrial Function and Redistributes Drp1 in Fibroblasts from Patients with Either Sporadic or Familial Alzheimer's Disease.
Bell, Simon M; Barnes, Katy; Clemmens, Hannah; Al-Rafiah, Aziza R; Al-Ofi, Ebtisam A; Leech, Vicki; Bandmann, Oliver; Shaw, Pamela J; Blackburn, Daniel J; Ferraiuolo, Laura; Mortiboys, Heather.
Affiliation
  • Bell SM; Sheffield Institute for Translational Neuroscience (SITraN), University of Sheffield, 385a Glossop Road, Sheffield, S10 2HQ, UK.
  • Barnes K; Sheffield Institute for Translational Neuroscience (SITraN), University of Sheffield, 385a Glossop Road, Sheffield, S10 2HQ, UK.
  • Clemmens H; Sheffield Institute for Translational Neuroscience (SITraN), University of Sheffield, 385a Glossop Road, Sheffield, S10 2HQ, UK.
  • Al-Rafiah AR; Sheffield Institute for Translational Neuroscience (SITraN), University of Sheffield, 385a Glossop Road, Sheffield, S10 2HQ, UK.
  • Al-Ofi EA; Sheffield Institute for Translational Neuroscience (SITraN), University of Sheffield, 385a Glossop Road, Sheffield, S10 2HQ, UK.
  • Leech V; Sheffield Institute for Translational Neuroscience (SITraN), University of Sheffield, 385a Glossop Road, Sheffield, S10 2HQ, UK.
  • Bandmann O; Sheffield Institute for Translational Neuroscience (SITraN), University of Sheffield, 385a Glossop Road, Sheffield, S10 2HQ, UK.
  • Shaw PJ; Sheffield Institute for Translational Neuroscience (SITraN), University of Sheffield, 385a Glossop Road, Sheffield, S10 2HQ, UK.
  • Blackburn DJ; Sheffield Institute for Translational Neuroscience (SITraN), University of Sheffield, 385a Glossop Road, Sheffield, S10 2HQ, UK.
  • Ferraiuolo L; Sheffield Institute for Translational Neuroscience (SITraN), University of Sheffield, 385a Glossop Road, Sheffield, S10 2HQ, UK.
  • Mortiboys H; Sheffield Institute for Translational Neuroscience (SITraN), University of Sheffield, 385a Glossop Road, Sheffield, S10 2HQ, UK. Electronic address: H.Mortiboys@sheffield.ac.uk.
J Mol Biol ; 430(21): 3942-3953, 2018 10 19.
Article in En | MEDLINE | ID: mdl-30171839
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ursodeoxycholic Acid / Mitochondrial Proteins / Alzheimer Disease / Fibroblasts / GTP Phosphohydrolases / Microtubule-Associated Proteins / Mitochondria Type of study: Etiology_studies Limits: Humans Language: En Journal: J Mol Biol Year: 2018 Document type: Article Affiliation country: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ursodeoxycholic Acid / Mitochondrial Proteins / Alzheimer Disease / Fibroblasts / GTP Phosphohydrolases / Microtubule-Associated Proteins / Mitochondria Type of study: Etiology_studies Limits: Humans Language: En Journal: J Mol Biol Year: 2018 Document type: Article Affiliation country: United kingdom