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Metabolism of c-Met Kinase Inhibitors Containing Quinoline by Aldehyde Oxidase, Electron Donating, and Steric Hindrance Effect.
Zhang, Jiang Wei; Xiao, Wen; Gao, Zhen Ting; Yu, Zheng Tian; Zhang, Ji Yue Jeff.
Affiliation
  • Zhang JW; China Novartis Institutes for BioMedical Research, Shanghai, People's Republic of China jiangwei.zhang@novartis.com jeff.zhang@novartis.com.
  • Xiao W; China Novartis Institutes for BioMedical Research, Shanghai, People's Republic of China.
  • Gao ZT; China Novartis Institutes for BioMedical Research, Shanghai, People's Republic of China.
  • Yu ZT; China Novartis Institutes for BioMedical Research, Shanghai, People's Republic of China.
  • Zhang JYJ; China Novartis Institutes for BioMedical Research, Shanghai, People's Republic of China jiangwei.zhang@novartis.com jeff.zhang@novartis.com.
Drug Metab Dispos ; 46(12): 1847-1855, 2018 12.
Article in En | MEDLINE | ID: mdl-30209037
Subject(s)
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Quinolines / Proto-Oncogene Proteins c-met / Cytosol / Aldehyde Oxidase / Protein Kinase Inhibitors / Liver Type of study: Prognostic_studies Limits: Animals / Humans / Male Language: En Journal: Drug Metab Dispos Journal subject: FARMACOLOGIA Year: 2018 Document type: Article Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Quinolines / Proto-Oncogene Proteins c-met / Cytosol / Aldehyde Oxidase / Protein Kinase Inhibitors / Liver Type of study: Prognostic_studies Limits: Animals / Humans / Male Language: En Journal: Drug Metab Dispos Journal subject: FARMACOLOGIA Year: 2018 Document type: Article Country of publication: United States