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Brugada syndrome trafficking-defective Nav1.5 channels can trap cardiac Kir2.1/2.2 channels.
Pérez-Hernández, Marta; Matamoros, Marcos; Alfayate, Silvia; Nieto-Marín, Paloma; Utrilla, Raquel G; Tinaquero, David; de Andrés, Raquel; Crespo, Teresa; Ponce-Balbuena, Daniela; Willis, B Cicero; Jiménez-Vazquez, Eric N; Guerrero-Serna, Guadalupe; da Rocha, Andre M; Campbell, Katherine; Herron, Todd J; Díez-Guerra, F Javier; Tamargo, Juan; Jalife, José; Caballero, Ricardo; Delpón, Eva.
Affiliation
  • Pérez-Hernández M; Department of Pharmacology and Toxicology, School of Medicine, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria Gregorio Marañón, and CIBER of Cardiovascular Diseases, Madrid, Spain.
  • Matamoros M; Department of Pharmacology and Toxicology, School of Medicine, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria Gregorio Marañón, and CIBER of Cardiovascular Diseases, Madrid, Spain.
  • Alfayate S; Department of Pharmacology and Toxicology, School of Medicine, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria Gregorio Marañón, and CIBER of Cardiovascular Diseases, Madrid, Spain.
  • Nieto-Marín P; Department of Pharmacology and Toxicology, School of Medicine, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria Gregorio Marañón, and CIBER of Cardiovascular Diseases, Madrid, Spain.
  • Utrilla RG; Department of Pharmacology and Toxicology, School of Medicine, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria Gregorio Marañón, and CIBER of Cardiovascular Diseases, Madrid, Spain.
  • Tinaquero D; Department of Pharmacology and Toxicology, School of Medicine, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria Gregorio Marañón, and CIBER of Cardiovascular Diseases, Madrid, Spain.
  • de Andrés R; Departamento de Biología Molecular and Centro de Biología Molecular "Severo Ochoa" (UAM-CSIC), Universidad Autónoma de Madrid, Madrid, Spain.
  • Crespo T; Department of Pharmacology and Toxicology, School of Medicine, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria Gregorio Marañón, and CIBER of Cardiovascular Diseases, Madrid, Spain.
  • Ponce-Balbuena D; Departments of Internal Medicine and Molecular and Integrative Physiology, Center for Arrhythmia Research, University of Michigan, Ann Arbor, Michigan, USA.
  • Willis BC; Departments of Internal Medicine and Molecular and Integrative Physiology, Center for Arrhythmia Research, University of Michigan, Ann Arbor, Michigan, USA.
  • Jiménez-Vazquez EN; Departments of Internal Medicine and Molecular and Integrative Physiology, Center for Arrhythmia Research, University of Michigan, Ann Arbor, Michigan, USA.
  • Guerrero-Serna G; Departments of Internal Medicine and Molecular and Integrative Physiology, Center for Arrhythmia Research, University of Michigan, Ann Arbor, Michigan, USA.
  • da Rocha AM; Departments of Internal Medicine and Molecular and Integrative Physiology, Center for Arrhythmia Research, University of Michigan, Ann Arbor, Michigan, USA.
  • Campbell K; Departments of Internal Medicine and Molecular and Integrative Physiology, Center for Arrhythmia Research, University of Michigan, Ann Arbor, Michigan, USA.
  • Herron TJ; Departments of Internal Medicine and Molecular and Integrative Physiology, Center for Arrhythmia Research, University of Michigan, Ann Arbor, Michigan, USA.
  • Díez-Guerra FJ; Departamento de Biología Molecular and Centro de Biología Molecular "Severo Ochoa" (UAM-CSIC), Universidad Autónoma de Madrid, Madrid, Spain.
  • Tamargo J; Department of Pharmacology and Toxicology, School of Medicine, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria Gregorio Marañón, and CIBER of Cardiovascular Diseases, Madrid, Spain.
  • Jalife J; Departments of Internal Medicine and Molecular and Integrative Physiology, Center for Arrhythmia Research, University of Michigan, Ann Arbor, Michigan, USA.
  • Caballero R; Fundación Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain.
  • Delpón E; Department of Pharmacology and Toxicology, School of Medicine, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria Gregorio Marañón, and CIBER of Cardiovascular Diseases, Madrid, Spain.
JCI Insight ; 3(18)2018 09 20.
Article in En | MEDLINE | ID: mdl-30232268
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Potassium Channels, Inwardly Rectifying / Brugada Syndrome / NAV1.5 Voltage-Gated Sodium Channel Limits: Animals / Humans / Male Language: En Journal: JCI Insight Year: 2018 Document type: Article Affiliation country: Spain Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Potassium Channels, Inwardly Rectifying / Brugada Syndrome / NAV1.5 Voltage-Gated Sodium Channel Limits: Animals / Humans / Male Language: En Journal: JCI Insight Year: 2018 Document type: Article Affiliation country: Spain Country of publication: United States