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Targeting heme Oxygenase-1 with hybrid compounds to overcome Imatinib resistance in chronic myeloid leukemia cell lines.
Sorrenti, Valeria; Pittalà, Valeria; Romeo, Giuseppe; Amata, Emanuele; Dichiara, Maria; Marrazzo, Agostino; Turnaturi, Rita; Prezzavento, Orazio; Barbagallo, Ignazio; Vanella, Luca; Rescifina, Antonio; Floresta, Giuseppe; Tibullo, Daniele; Di Raimondo, Francesco; Intagliata, Sebastiano; Salerno, Loredana.
Affiliation
  • Sorrenti V; Department of Drug Sciences, University of Catania, viale A. Doria 6, 95125, Catania, Italy.
  • Pittalà V; Department of Drug Sciences, University of Catania, viale A. Doria 6, 95125, Catania, Italy. Electronic address: vpittala@unict.it.
  • Romeo G; Department of Drug Sciences, University of Catania, viale A. Doria 6, 95125, Catania, Italy.
  • Amata E; Department of Drug Sciences, University of Catania, viale A. Doria 6, 95125, Catania, Italy.
  • Dichiara M; Department of Drug Sciences, University of Catania, viale A. Doria 6, 95125, Catania, Italy.
  • Marrazzo A; Department of Drug Sciences, University of Catania, viale A. Doria 6, 95125, Catania, Italy.
  • Turnaturi R; Department of Drug Sciences, University of Catania, viale A. Doria 6, 95125, Catania, Italy.
  • Prezzavento O; Department of Drug Sciences, University of Catania, viale A. Doria 6, 95125, Catania, Italy.
  • Barbagallo I; Department of Drug Sciences, University of Catania, viale A. Doria 6, 95125, Catania, Italy.
  • Vanella L; Department of Drug Sciences, University of Catania, viale A. Doria 6, 95125, Catania, Italy.
  • Rescifina A; Department of Drug Sciences, University of Catania, viale A. Doria 6, 95125, Catania, Italy.
  • Floresta G; Department of Drug Sciences, University of Catania, viale A. Doria 6, 95125, Catania, Italy; Department of Chemical Sciences, University of Catania, viale A. Doria 6, 95125, Catania, Italy.
  • Tibullo D; Division of Hematology, A.O.U. Policlinico-OVE, University of Catania, via S. Sofia, 78, 95123, Catania, Italy; Department of Biomedical and Biotechnological Sciences, University of Catania, via S. Sofia, 78, 95123, Catania, Italy.
  • Di Raimondo F; Division of Hematology, A.O.U. Policlinico-OVE, University of Catania, via S. Sofia, 78, 95123, Catania, Italy.
  • Intagliata S; Department of Medicinal Chemistry, College of Pharmacy, University of Florida, Gainesville, FL, USA.
  • Salerno L; Department of Drug Sciences, University of Catania, viale A. Doria 6, 95125, Catania, Italy. Electronic address: l.salerno@unict.it.
Eur J Med Chem ; 158: 937-950, 2018 Oct 05.
Article in En | MEDLINE | ID: mdl-30261468
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Heme Oxygenase-1 / Imatinib Mesylate / Imidazoles / Antineoplastic Agents Type of study: Prognostic_studies Limits: Humans Language: En Journal: Eur J Med Chem Year: 2018 Document type: Article Affiliation country: Italy Country of publication: France
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Heme Oxygenase-1 / Imatinib Mesylate / Imidazoles / Antineoplastic Agents Type of study: Prognostic_studies Limits: Humans Language: En Journal: Eur J Med Chem Year: 2018 Document type: Article Affiliation country: Italy Country of publication: France