Multiple cellular neurothekeomas in a middle-aged woman including the lower extremity: A case report and review of the current literature.
J Cutan Pathol
; 46(1): 67-73, 2019 Jan.
Article
in En
| MEDLINE
| ID: mdl-30270462
ABSTRACT
Cellular neurothekeoma is a benign cutaneous neoplasm that typically occurs on the head, neck, and upper body of young adults with a slight female predominance. It is a rare lesion to diagnose and multiple neurothekeomas in one patient are even more uncommon finding. We present a case of multiple neurothekeomas in a middle-aged woman with lower extremity involvement and summarize the current literature on multiple neurothekeoma patients. A 46-year-old female presented with nearly one dozen skin-colored papules on the head, upper limb, and lower limb. The lesions were clinically diagnosed as dermatofibromas and a nevus. Eight lesions were biopsied and confirmed to be cellular neurothekeomas, with one initially misinterpreted on histology as a dermatofibroma. Awareness of cellular neurothekeoma as a diagnostic entity and the possibility of atypical presentations as seen in our case (eg, in multiple numbers, in older adults, and on the lower extremity) are important in allowing for accurate clinical and histological diagnosis of these lesions. The possibility of a syndromic association with multiple cellular neurothekeomas should be explored further.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Skin Neoplasms
/
Neurothekeoma
/
Lower Extremity
Type of study:
Diagnostic_studies
Limits:
Humans
/
Middle aged
Language:
En
Journal:
J Cutan Pathol
Year:
2019
Document type:
Article
Affiliation country:
Canada