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Non-NAD-like PARP1 inhibitor enhanced synthetic lethal effect of NAD-like PARP inhibitors against BRCA1-deficient leukemia.
Nieborowska-Skorska, Margaret; Maifrede, Silvia; Ye, Min; Toma, Monika; Hewlett, Elizabeth; Gordon, John; Le, Bac Viet; Sliwinski, Tomasz; Zhao, Huaqing; Piwocka, Katarzyna; Valent, Peter; Tulin, Alexei V; Childers, Wayne; Skorski, Tomasz.
Affiliation
  • Nieborowska-Skorska M; a Department of Microbiology and Immunology and Fels Institute for Cancer Research and Molecular Biology Lewis Katz School of Medicine , Temple University , Philadelphia , PA , USA.
  • Maifrede S; a Department of Microbiology and Immunology and Fels Institute for Cancer Research and Molecular Biology Lewis Katz School of Medicine , Temple University , Philadelphia , PA , USA.
  • Ye M; b Temple University School of Pharmacy, Moulder Center for Drug Discovery Research , Philadelphia , PA , USA.
  • Toma M; a Department of Microbiology and Immunology and Fels Institute for Cancer Research and Molecular Biology Lewis Katz School of Medicine , Temple University , Philadelphia , PA , USA.
  • Hewlett E; c Laboratory of Medical Genetics Faculty of Biology and Environmental Protection , University of Lodz , Lodz , Poland.
  • Gordon J; b Temple University School of Pharmacy, Moulder Center for Drug Discovery Research , Philadelphia , PA , USA.
  • Le BV; b Temple University School of Pharmacy, Moulder Center for Drug Discovery Research , Philadelphia , PA , USA.
  • Sliwinski T; a Department of Microbiology and Immunology and Fels Institute for Cancer Research and Molecular Biology Lewis Katz School of Medicine , Temple University , Philadelphia , PA , USA.
  • Zhao H; d Laboratory of Cytometry , Nencki Institute of Experimental Biology , Warsaw , Poland.
  • Piwocka K; c Laboratory of Medical Genetics Faculty of Biology and Environmental Protection , University of Lodz , Lodz , Poland.
  • Valent P; e Department of Clinical Sciences Lewis Katz School of Medicine , Temple University , Philadelphia , PA , USA.
  • Tulin AV; d Laboratory of Cytometry , Nencki Institute of Experimental Biology , Warsaw , Poland.
  • Childers W; f Department of Internal Medicine I Division of Hematology & Hemostaseology and Ludwig-Boltzmann Cluster Oncology , Medical University of Vienna , Austria , Vienna.
  • Skorski T; g Department of Biomedical Sciences School of Medicine and Health Sciences , University of North Dakota , Grand Forks , ND , USA.
Leuk Lymphoma ; 60(4): 1098-1101, 2019 04.
Article in En | MEDLINE | ID: mdl-30277116
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia / BRCA1 Protein / Poly(ADP-ribose) Polymerase Inhibitors / Synthetic Lethal Mutations Limits: Humans Language: En Journal: Leuk Lymphoma Journal subject: HEMATOLOGIA / NEOPLASIAS Year: 2019 Document type: Article Affiliation country: United States Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia / BRCA1 Protein / Poly(ADP-ribose) Polymerase Inhibitors / Synthetic Lethal Mutations Limits: Humans Language: En Journal: Leuk Lymphoma Journal subject: HEMATOLOGIA / NEOPLASIAS Year: 2019 Document type: Article Affiliation country: United States Country of publication: United States