rTMS pre-treatment effectively protects against cognitive and synaptic plasticity impairments induced by simulated microgravity in mice.

Xiang, Shitong; Zhou, Yu; Fu, Jingxuan; Zhang, Tao

Xiang, Shitong; Zhou, Yu; Fu, Jingxuan; Zhang, Tao.

Affiliation

Xiang S; College of Life Sciences and Key Laboratory of Bioactive Materials Ministry of Education, Nankai University, 300071 Tianjin, PR China.
Zhou Y; College of Life Sciences and Key Laboratory of Bioactive Materials Ministry of Education, Nankai University, 300071 Tianjin, PR China.
Fu J; College of Life Sciences and Key Laboratory of Bioactive Materials Ministry of Education, Nankai University, 300071 Tianjin, PR China.
Zhang T; College of Life Sciences and Key Laboratory of Bioactive Materials Ministry of Education, Nankai University, 300071 Tianjin, PR China. Electronic address: zhangtao@nankai.edu.cn.

Behav Brain Res ; 359: 639-647, 2019 02 01.

Article in En | MEDLINE | ID: mdl-30292903

Subject(s)

Cognitive Dysfunction/etiology; Cognitive Dysfunction/prevention & control; Neuronal Plasticity; Transcranial Magnetic Stimulation; Weightlessness Countermeasures; Weightlessness Simulation/adverse effects; Animals; Brain-Derived Neurotrophic Factor/metabolism; Cyclic AMP Response Element-Binding Protein/metabolism; Hippocampus/pathology; Hippocampus/physiopathology; Male; Mice, Inbred C57BL; Random Allocation; Recognition, Psychology

Key words

BDNF; CREB; Cognition function; Microgravity; Synaptic plasticity; rTMS

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Weightlessness Simulation / Weightlessness Countermeasures / Transcranial Magnetic Stimulation / Cognitive Dysfunction / Neuronal Plasticity Type of study: Prognostic_studies Limits: Animals Language: En Journal: Behav Brain Res Year: 2019 Document type: Article Country of publication: Netherlands

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