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Rapamycin and FK506 derivative TH2849 could ameliorate neurodegenerative diseases through autophagy with low immunosuppressive effect.
Ding, Li; Nan, Wen-Hao; Zhu, Xian-Bing; Li, Xiao-Ming; Zhou, Li-Yan; Chen, Hou-Jie; Yu, Lu; Ullah Khan, Fahim; Zhong, Han-Bing; Shi, Xiao-Jun.
Affiliation
  • Ding L; School of Life Sciences, Tsinghua University, Beijing, China.
  • Nan WH; Graduate School at Shenzhen, Tsinghua University, Shenzhen, China.
  • Zhu XB; School of Life Sciences, Tsinghua University, Beijing, China.
  • Li XM; Graduate School at Shenzhen, Tsinghua University, Shenzhen, China.
  • Zhou LY; School of Life Sciences, Tsinghua University, Beijing, China.
  • Chen HJ; Graduate School at Shenzhen, Tsinghua University, Shenzhen, China.
  • Yu L; Department of Biochemistry, Rosalind and Morris Goodman Cancer Research Center, McGill University, Montreal, QC, Canada.
  • Ullah Khan F; School of Life Sciences, Tsinghua University, Beijing, China.
  • Zhong HB; Graduate School at Shenzhen, Tsinghua University, Shenzhen, China.
  • Shi XJ; Laboratory of Chemical Genomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Shenzhen, China.
CNS Neurosci Ther ; 25(4): 452-464, 2019 04.
Article in En | MEDLINE | ID: mdl-30294901
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autophagy / Tacrolimus / Sirolimus / MPTP Poisoning / Immunosuppressive Agents Limits: Animals Language: En Journal: CNS Neurosci Ther Journal subject: NEUROLOGIA / TERAPEUTICA Year: 2019 Document type: Article Affiliation country: China Country of publication: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autophagy / Tacrolimus / Sirolimus / MPTP Poisoning / Immunosuppressive Agents Limits: Animals Language: En Journal: CNS Neurosci Ther Journal subject: NEUROLOGIA / TERAPEUTICA Year: 2019 Document type: Article Affiliation country: China Country of publication: United kingdom