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Neratinib is effective in breast tumors bearing both amplification and mutation of ERBB2 (HER2).
Cocco, Emiliano; Javier Carmona, F; Razavi, Pedram; Won, Helen H; Cai, Yanyan; Rossi, Valentina; Chan, Carmen; Cownie, James; Soong, Joanne; Toska, Eneda; Shifman, Sophie G; Sarotto, Ivana; Savas, Peter; Wick, Michael J; Papadopoulos, Kyriakos P; Moriarty, Alyssa; Cutler, Richard E; Avogadri-Connors, Francesca; Lalani, Alshad S; Bryce, Richard P; Chandarlapaty, Sarat; Hyman, David M; Solit, David B; Boni, Valentina; Loi, Sherene; Baselga, José; Berger, Michael F; Montemurro, Filippo; Scaltriti, Maurizio.
Affiliation
  • Cocco E; Human Oncology & Pathogenesis Program (HOPP), Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.
  • Javier Carmona F; Human Oncology & Pathogenesis Program (HOPP), Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.
  • Razavi P; Human Oncology & Pathogenesis Program (HOPP), Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.
  • Won HH; Department of Medicine, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.
  • Cai Y; Human Oncology & Pathogenesis Program (HOPP), Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.
  • Rossi V; Department of Pathology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.
  • Chan C; Human Oncology & Pathogenesis Program (HOPP), Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.
  • Cownie J; Department of Pathology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.
  • Soong J; Unit of Investigative Clinical Oncology (INCO), Candiolo Cancer Institute, FPO-IRCCS, Str. Provinciale 142, 10060 Candiolo, Italy.
  • Toska E; Human Oncology & Pathogenesis Program (HOPP), Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.
  • Shifman SG; Human Oncology & Pathogenesis Program (HOPP), Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.
  • Sarotto I; Human Oncology & Pathogenesis Program (HOPP), Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.
  • Savas P; Human Oncology & Pathogenesis Program (HOPP), Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.
  • Wick MJ; Human Oncology & Pathogenesis Program (HOPP), Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.
  • Papadopoulos KP; Unit of Surgical Pathology, Fondazione del Piemonte per l'Oncologia, Candiolo Cancer Institute, FPO-IRCCS, Str. Provinciale 142, 10060 Candiolo, Italy.
  • Moriarty A; Division of Research and Cancer Medicine, Peter MacCallum Cancer Centre, University of Melbourne, Melbourne, VIC 3000, Australia.
  • Cutler RE; START, 4383 Medical Dr, San Antonio, TX 78229, USA.
  • Avogadri-Connors F; START, 4383 Medical Dr, San Antonio, TX 78229, USA.
  • Lalani AS; START, 4383 Medical Dr, San Antonio, TX 78229, USA.
  • Bryce RP; Puma Biotechnology Inc., 10880 Wilshire Blvd, Los Angeles, CA 90024, USA.
  • Chandarlapaty S; Puma Biotechnology Inc., 10880 Wilshire Blvd, Los Angeles, CA 90024, USA.
  • Hyman DM; Puma Biotechnology Inc., 10880 Wilshire Blvd, Los Angeles, CA 90024, USA.
  • Solit DB; Puma Biotechnology Inc., 10880 Wilshire Blvd, Los Angeles, CA 90024, USA.
  • Boni V; Human Oncology & Pathogenesis Program (HOPP), Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.
  • Loi S; Department of Medicine, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.
  • Baselga J; Department of Medicine, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.
  • Berger MF; Human Oncology & Pathogenesis Program (HOPP), Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.
  • Montemurro F; Department of Medicine, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.
  • Scaltriti M; Marie-Josée and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.
Sci Signal ; 11(551)2018 10 09.
Article in En | MEDLINE | ID: mdl-30301790
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Quinolines / Breast Neoplasms / Receptor, ErbB-2 / Protein Kinase Inhibitors / Antineoplastic Agents Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Sci Signal Journal subject: CIENCIA / FISIOLOGIA Year: 2018 Document type: Article Affiliation country: United States Country of publication: United States
Fulltext
Add to My VHL
Print
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Quinolines / Breast Neoplasms / Receptor, ErbB-2 / Protein Kinase Inhibitors / Antineoplastic Agents Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Sci Signal Journal subject: CIENCIA / FISIOLOGIA Year: 2018 Document type: Article Affiliation country: United States Country of publication: United States