Consensus designs and thermal stability determinants of a human glutamate transporter.

Cirri, Erica; Brier, Sébastien; Assal, Reda; Canul-Tec, Juan Carlos; Chamot-Rooke, Julia; Reyes, Nicolas

Cirri, Erica; Brier, Sébastien; Assal, Reda; Canul-Tec, Juan Carlos; Chamot-Rooke, Julia; Reyes, Nicolas.

Affiliation

Cirri E; Molecular Mechanisms of Membrane Transport Laboratory, Institut Pasteur, Paris, France.
Brier S; UMR 3528, CNRS, Institut Pasteur, Paris, France.
Assal R; Mass Spectrometry for Biology Unit, Institut Pasteur, Paris, France.
Canul-Tec JC; USR 2000, CNRS, Institut Pasteur, Paris, France.
Chamot-Rooke J; Molecular Mechanisms of Membrane Transport Laboratory, Institut Pasteur, Paris, France.
Reyes N; UMR 3528, CNRS, Institut Pasteur, Paris, France.

Elife ; 72018 10 18.

Article in En | MEDLINE | ID: mdl-30334738

Subject(s)

Amino Acid Transport System X-AG/chemistry; Amino Acid Transport System X-AG/metabolism; Consensus Sequence; Excitatory Amino Acid Transporter 1/chemistry; Excitatory Amino Acid Transporter 1/metabolism; Temperature; Amino Acid Sequence; Deuterium Exchange Measurement; Humans; Kinetics; Models, Molecular; Mutant Proteins/chemistry; Neurotransmitter Agents/metabolism; Protein Stability; Protein Subunits/chemistry; Protein Unfolding

Key words

biochemistry; chemical biology; consensus amino acid; human; molecular biophysics; permeation and transport; protein dynamics; protein folding; protein stability; structural biology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Temperature / Consensus Sequence / Amino Acid Transport System X-AG / Excitatory Amino Acid Transporter 1 Type of study: Prognostic_studies Limits: Humans Language: En Journal: Elife Year: 2018 Document type: Article Affiliation country: France Country of publication: United kingdom

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