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Identification of a novel cytochrome P450 enzyme that catalyzes the C-2α hydroxylation of pentacyclic triterpenoids and its application in yeast cell factories.
Dai, Zhubo; Liu, Yun; Sun, Zhoutong; Wang, Dong; Qu, Ge; Ma, Xiaolin; Fan, Feiyu; Zhang, Lili; Li, Shoulian; Zhang, Xueli.
Affiliation
  • Dai Z; Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, China; Key Laboratory of Systems Microbial Biotechnology, Chinese Academy of Sciences, China.
  • Liu Y; Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, China; Key Laboratory of Systems Microbial Biotechnology, Chinese Academy of Sciences, China.
  • Sun Z; Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, China.
  • Wang D; Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, China; Key Laboratory of Systems Microbial Biotechnology, Chinese Academy of Sciences, China.
  • Qu G; Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, China.
  • Ma X; Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, China; College of Biotechnology, Tianjin University of Science and Technology, China.
  • Fan F; Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, China; Key Laboratory of Systems Microbial Biotechnology, Chinese Academy of Sciences, China.
  • Zhang L; Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, China; College of Biotechnology, Tianjin University of Science and Technology, China.
  • Li S; Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, China; College of Biotechnology, Tianjin University of Science and Technology, China.
  • Zhang X; Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, China; Key Laboratory of Systems Microbial Biotechnology, Chinese Academy of Sciences, China. Electronic address: zhang_xl@tib.cas.cn.
Metab Eng ; 51: 70-78, 2019 01.
Article in En | MEDLINE | ID: mdl-30339834
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Saccharomyces cerevisiae / Triterpenes / Cytochrome P-450 Enzyme System Type of study: Diagnostic_studies / Prognostic_studies Language: En Journal: Metab Eng Journal subject: ENGENHARIA BIOMEDICA / METABOLISMO Year: 2019 Document type: Article Affiliation country: China Country of publication: Belgium
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Saccharomyces cerevisiae / Triterpenes / Cytochrome P-450 Enzyme System Type of study: Diagnostic_studies / Prognostic_studies Language: En Journal: Metab Eng Journal subject: ENGENHARIA BIOMEDICA / METABOLISMO Year: 2019 Document type: Article Affiliation country: China Country of publication: Belgium