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An effective "three-in-one" screening assay for testing drug and nanoparticle toxicity in human endothelial cells.
Filipova, Marcela; Elhelu, Oumsalama K; De Paoli, Silvia H; Fremuntova, Zuzana; Mosko, Tibor; Cmarko, Dusan; Simak, Jan; Holada, Karel.
Affiliation
  • Filipova M; Institute of Immunology and Microbiology, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czech Republic.
  • Elhelu OK; Department of Biological Models, Institute of Macromolecular Chemistry, Academy of Sciences of the Czech Republic, v.v.i., Prague, Czech Republic.
  • De Paoli SH; Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland, United States of America.
  • Fremuntova Z; Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland, United States of America.
  • Mosko T; Institute of Immunology and Microbiology, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czech Republic.
  • Cmarko D; Institute of Immunology and Microbiology, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czech Republic.
  • Simak J; Institute of Biology and Medical Genetics, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czech Republic.
  • Holada K; Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland, United States of America.
PLoS One ; 13(10): e0206557, 2018.
Article in En | MEDLINE | ID: mdl-30379903

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cell Survival / Apoptosis / Endothelial Cells / Drug Evaluation, Preclinical / Nanoparticles Type of study: Diagnostic_studies / Screening_studies Limits: Humans Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2018 Document type: Article Affiliation country: Czech Republic

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cell Survival / Apoptosis / Endothelial Cells / Drug Evaluation, Preclinical / Nanoparticles Type of study: Diagnostic_studies / Screening_studies Limits: Humans Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2018 Document type: Article Affiliation country: Czech Republic