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Synthesis and anti-proliferative activity of some new quinoline based 4,5-dihydropyrazoles and their thiazole hybrids as EGFR inhibitors.
George, Riham F; Samir, Eman M; Abdelhamed, Mennatullah N; Abdel-Aziz, Hatem A; Abbas, Safinaz E-S.
Affiliation
  • George RF; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Cairo University, Cairo 11562, Egypt. Electronic address: riham.eskandar@pharma.cu.edu.eg.
  • Samir EM; Organic Chemistry Department, National Organization For Drug & Control Research, Cairo, Egypt.
  • Abdelhamed MN; Organic Chemistry Department, National Organization For Drug & Control Research, Cairo, Egypt.
  • Abdel-Aziz HA; Department of Applied Organic Chemistry, National Research Center, Dokki, P.O. Box 12622, Giza, Egypt.
  • Abbas SE; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Cairo University, Cairo 11562, Egypt.
Bioorg Chem ; 83: 186-197, 2019 03.
Article in En | MEDLINE | ID: mdl-30380447
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrazoles / Quinolines / Thiazoles / Protein Kinase Inhibitors / Antineoplastic Agents Limits: Humans Language: En Journal: Bioorg Chem Year: 2019 Document type: Article Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrazoles / Quinolines / Thiazoles / Protein Kinase Inhibitors / Antineoplastic Agents Limits: Humans Language: En Journal: Bioorg Chem Year: 2019 Document type: Article Country of publication: United States