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Identification and quantification of product-related quality attributes in bio-therapeutic monoclonal antibody via a simple, and robust cation-exchange HPLC method compatible with direct online detection of UV and native ESI-QTOF-MS analysis.
Sankaran, Praveen Kallamvalliillam; Kabadi, Pradeep G; Honnappa, Chethan Gejjalagere; Subbarao, Malini; Pai, Harish V; Adhikary, Laxmi; Palanivelu, Dinesh V.
Affiliation
  • Sankaran PK; Molecular Characterization Laboratory, Biocon Research Limited, Biocon Limited, Biocon Park, Bommasandra - Jigani Link Road, Bommasandra Industrial Area Phase IV, Bangalore 560099, India. Electronic address: pharmacistpravi@gmail.com.
  • Kabadi PG; Molecular Characterization Laboratory, Biocon Research Limited, Biocon Limited, Biocon Park, Bommasandra - Jigani Link Road, Bommasandra Industrial Area Phase IV, Bangalore 560099, India.
  • Honnappa CG; Molecular Characterization Laboratory, Biocon Research Limited, Biocon Limited, Biocon Park, Bommasandra - Jigani Link Road, Bommasandra Industrial Area Phase IV, Bangalore 560099, India.
  • Subbarao M; Bioassay Development Laboratory, Biocon Research Limited, Biocon Limited, Biocon Park, Bommasandra - Jigani Link Road, Bommasandra Industrial Area Phase IV, Bangalore 560099, India.
  • Pai HV; Bioassay Development Laboratory, Biocon Research Limited, Biocon Limited, Biocon Park, Bommasandra - Jigani Link Road, Bommasandra Industrial Area Phase IV, Bangalore 560099, India.
  • Adhikary L; Molecular Characterization Laboratory, Biocon Research Limited, Biocon Limited, Biocon Park, Bommasandra - Jigani Link Road, Bommasandra Industrial Area Phase IV, Bangalore 560099, India.
  • Palanivelu DV; Molecular Characterization Laboratory, Biocon Research Limited, Biocon Limited, Biocon Park, Bommasandra - Jigani Link Road, Bommasandra Industrial Area Phase IV, Bangalore 560099, India.
J Chromatogr B Analyt Technol Biomed Life Sci ; 1102-1103: 83-95, 2018 Dec 01.
Article in En | MEDLINE | ID: mdl-30380467
Subject(s)
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Chromatography, High Pressure Liquid / Chromatography, Ion Exchange / Spectrometry, Mass, Electrospray Ionization / Antibodies, Monoclonal Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals / Humans Language: En Journal: J Chromatogr B Analyt Technol Biomed Life Sci Journal subject: ENGENHARIA BIOMEDICA Year: 2018 Document type: Article Country of publication: Netherlands
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Chromatography, High Pressure Liquid / Chromatography, Ion Exchange / Spectrometry, Mass, Electrospray Ionization / Antibodies, Monoclonal Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals / Humans Language: En Journal: J Chromatogr B Analyt Technol Biomed Life Sci Journal subject: ENGENHARIA BIOMEDICA Year: 2018 Document type: Article Country of publication: Netherlands