Stability and compatibility of Basmisanil granules co-administered with soft food.

Szepes, Anikó; Pabst-Ravot, Anni; Storch, Kirsten; Timpe, Carsten

Szepes, Anikó; Pabst-Ravot, Anni; Storch, Kirsten; Timpe, Carsten.

Affiliation

Szepes A; F. Hoffmann-La Roche Ltd., Formulation Research & Development, Basel, Switzerland. Electronic address: aniko.szepes@roche.com.
Pabst-Ravot A; F. Hoffmann-La Roche Ltd., Analytical Development, Basel, Switzerland.
Storch K; F. Hoffmann-La Roche Ltd., Analytical Development, Basel, Switzerland.
Timpe C; F. Hoffmann-La Roche Ltd., Formulation Research & Development, Basel, Switzerland.

Int J Pharm ; 553(1-2): 422-427, 2018 Dec 20.

Article in En | MEDLINE | ID: mdl-30393169

Subject(s)

Chemistry, Pharmaceutical/methods; Food-Drug Interactions; GABA-A Receptor Antagonists/administration & dosage; Administration, Oral; Drug Liberation; Drug Storage; Food; GABA-A Receptor Antagonists/chemistry; Hydrogen-Ion Concentration; Time Factors

Key words

Basmisanil; Dissolution; Food compatibility; Oral drug delivery; Stability

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Chemistry, Pharmaceutical / Food-Drug Interactions / GABA-A Receptor Antagonists Language: En Journal: Int J Pharm Year: 2018 Document type: Article Country of publication: Netherlands

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