Choledochal malformations: global research, scientific advances and key controversies.
Pediatr Surg Int
; 35(3): 273-282, 2019 Mar.
Article
in En
| MEDLINE
| ID: mdl-30406431
Choledochal malformations (CMs) represent a spectrum of relatively rare and complex congenital anomalies, characterized by abnormal dilatation of the biliary tract in the absence of any acute obstruction. Today, almost 20% of CMs can be detected in-utero using maternal ultrasonography. Formal scientometric analysis was used to identify where modern CM research is taking place and perhaps where our attention should be directed in the future. Thus, this article offers a comprehensive review of recent scientific advances relating to CMs including the current understanding of etiology and classification, whilst also discussing key controversies such as risk of malignant transformation and the role of newer modalities of surgical treatment. Although laparoscopic excision of CMs and biliary reconstruction is nowadays feasible and safe, care should be taken before dispensing with standard open techniques, which have minimal complication rates and proven long-term benefit.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Choledochal Cyst
/
Common Bile Duct
/
Biomedical Research
/
Gastroenterology
Type of study:
Diagnostic_studies
/
Incidence_studies
/
Prognostic_studies
Limits:
Humans
Language:
En
Journal:
Pediatr Surg Int
Journal subject:
PEDIATRIA
Year:
2019
Document type:
Article
Country of publication:
Germany