Acyl atractyligenin and carboxyatractyligenin glycosides from Antennaria rosea subsp. confinis.
Phytochemistry
; 157: 151-157, 2019 Jan.
Article
in En
| MEDLINE
| ID: mdl-30408728
Eight previously undescribed acyl atractyligenin and carboxyatractyligenin glycosides were isolated from whole Antennaria rosea subsp. confinis (Greene) R. J. Bayer (Compositae) [syn. Leontopodium leontopodioides (Willd.) Beauv. (Asteraceae)] plants and their structures were determined by spectroscopic and chemical methods. The compounds were trivially named leontopodiosides F-M. Seven of the compounds showed potent in vitro inhibitory activity toward pancreatic lipase with IC50 values ranging from 3.4 to 52.5⯵M, suggesting that they participate in the previously observed effect this plant has in reducing triglyceride absorption in rats.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Atractyloside
/
Asteraceae
/
Glycoside Hydrolase Inhibitors
/
Glycosides
Limits:
Animals
Language:
En
Journal:
Phytochemistry
Year:
2019
Document type:
Article
Affiliation country:
China
Country of publication:
United kingdom