Modulation of Mutant KrasG12D -Driven Lung Tumorigenesis In Vivo by Gain or Loss of PCDH7 Function.

Zhou, Xiaorong; Padanad, Mahesh S; Evers, Bret M; Smith, Bethany; Novaresi, Nicole; Suresh, Shruthy; Richardson, James A; Stein, Emily; Zhu, Jingfei; Hammer, Robert E; O'Donnell, Kathryn A

Modulation of Mutant Kras^G12D -Driven Lung Tumorigenesis In Vivo by Gain or Loss of PCDH7 Function.

Zhou, Xiaorong; Padanad, Mahesh S; Evers, Bret M; Smith, Bethany; Novaresi, Nicole; Suresh, Shruthy; Richardson, James A; Stein, Emily; Zhu, Jingfei; Hammer, Robert E; O'Donnell, Kathryn A.

Affiliation

Zhou X; Department of Molecular Biology, UT Southwestern Medical Center, Dallas, Texas.
Padanad MS; Department of Immunology, Nantong University School of Medicine, Nantong, China.
Evers BM; Department of Molecular Biology, UT Southwestern Medical Center, Dallas, Texas.
Smith B; Department of Pathology, UT Southwestern Medical Center, Dallas, Texas.
Novaresi N; Department of Molecular Biology, UT Southwestern Medical Center, Dallas, Texas.
Suresh S; Department of Molecular Biology, UT Southwestern Medical Center, Dallas, Texas.
Richardson JA; Department of Molecular Biology, UT Southwestern Medical Center, Dallas, Texas.
Stein E; Department of Molecular Biology, UT Southwestern Medical Center, Dallas, Texas.
Zhu J; Department of Pathology, UT Southwestern Medical Center, Dallas, Texas.
Hammer RE; Department of Molecular Biology, UT Southwestern Medical Center, Dallas, Texas.
O'Donnell KA; Department of Molecular Biology, UT Southwestern Medical Center, Dallas, Texas.

Mol Cancer Res ; 17(2): 594-603, 2019 02.

Article in En | MEDLINE | ID: mdl-30409919

Subject(s)

Adenocarcinoma of Lung/genetics; Cadherins/genetics; Lung Neoplasms/genetics; Proto-Oncogene Proteins p21(ras)/genetics; Adenocarcinoma of Lung/metabolism; Adenocarcinoma of Lung/pathology; Animals; Cadherins/deficiency; Cadherins/metabolism; Carcinogenesis; Humans; Lung Neoplasms/metabolism; Lung Neoplasms/pathology; MAP Kinase Signaling System; Mice; Mice, Transgenic; Proto-Oncogene Proteins p21(ras)/metabolism; Protocadherins; Signal Transduction

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cadherins / Proto-Oncogene Proteins p21(ras) / Adenocarcinoma of Lung / Lung Neoplasms Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Mol Cancer Res Journal subject: BIOLOGIA MOLECULAR / NEOPLASIAS Year: 2019 Document type: Article

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