Donor derived HSV hepatitis in a kidney transplant recipient leading to liver fibrosis and portal hypertension.
Transpl Infect Dis
; 21(1): e13029, 2019 Feb.
Article
in En
| MEDLINE
| ID: mdl-30431215
ABSTRACT
The unexpected transmission of donor-derived infection through organ transplantation is a rare event with current donor screening practices. In this case report we describe a probable donor-derived transmission of Herpes Simplex Virus (HSV)-2 via deceased donor kidney transplantation resulting in HSV hepatitis in the recipient. This manifested as acute liver failure which resolved with appropriate anti-viral therapy. Following recovery from the acute liver insult, the patient developed fibrotic liver morphology and portal hypertension, an unusual departure from the typical course.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Kidney Transplantation
/
Liver Failure, Acute
/
Hepatitis, Viral, Human
/
Herpes Simplex
/
Hypertension, Portal
/
Liver Cirrhosis
Type of study:
Diagnostic_studies
Limits:
Adult
/
Female
/
Humans
Language:
En
Journal:
Transpl Infect Dis
Journal subject:
TRANSPLANTE
Year:
2019
Document type:
Article