Optimization of high-dose methotrexate with leucovorin rescue therapy in the L1210 leukemia and sarcoma 180 murine tumor models.

Sirotnak, F M; Moccio, D M; Dorick, D M

Sirotnak, F M; Moccio, D M; Dorick, D M.

Cancer Res ; 38(2): 345-53, 1978 Feb.

Article in En | MEDLINE | ID: mdl-304375

Subject(s)

Leucovorin/therapeutic use; Leukemia L1210/drug therapy; Methotrexate/toxicity; Sarcoma 180/drug therapy; Animals; Calcium; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Leucovorin/administration & dosage; Leukemia L1210/mortality; Methotrexate/administration & dosage; Methotrexate/therapeutic use; Mice; Mice, Inbred Strains; Sarcoma 180/mortality; Time Factors

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Collection: 01-internacional Database: MEDLINE Main subject: Sarcoma 180 / Leukemia L1210 / Methotrexate / Leucovorin Type of study: Prognostic_studies Limits: Animals Language: En Journal: Cancer Res Year: 1978 Document type: Article Country of publication: United States

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