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Orthogonal Cas9-Cas9 chimeras provide a versatile platform for genome editing.
Bolukbasi, Mehmet Fatih; Liu, Pengpeng; Luk, Kevin; Kwok, Samantha F; Gupta, Ankit; Amrani, Nadia; Sontheimer, Erik J; Zhu, Lihua Julie; Wolfe, Scot A.
Affiliation
  • Bolukbasi MF; Department of Molecular, Cell and Cancer Biology, University of Massachusetts Medical School, Worcester, MA, USA.
  • Liu P; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA, USA.
  • Luk K; Exonics Therapeutics, Watertown, MA, USA.
  • Kwok SF; Department of Molecular, Cell and Cancer Biology, University of Massachusetts Medical School, Worcester, MA, USA.
  • Gupta A; Department of Molecular, Cell and Cancer Biology, University of Massachusetts Medical School, Worcester, MA, USA.
  • Amrani N; Department of Molecular, Cell and Cancer Biology, University of Massachusetts Medical School, Worcester, MA, USA.
  • Sontheimer EJ; Department of Molecular, Cell and Cancer Biology, University of Massachusetts Medical School, Worcester, MA, USA.
  • Zhu LJ; Bluebird Bio., Cambridge, MA, USA.
  • Wolfe SA; RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, MA, USA.
Nat Commun ; 9(1): 4856, 2018 11 19.
Article in En | MEDLINE | ID: mdl-30451839
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bacterial Proteins / Base Sequence / Sequence Deletion / Endonucleases / Mutant Chimeric Proteins / CRISPR-Cas Systems / Gene Editing Type of study: Prognostic_studies Limits: Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2018 Document type: Article Affiliation country: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bacterial Proteins / Base Sequence / Sequence Deletion / Endonucleases / Mutant Chimeric Proteins / CRISPR-Cas Systems / Gene Editing Type of study: Prognostic_studies Limits: Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2018 Document type: Article Affiliation country: United States