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Chemo- and Regioselective Dihydroxylation of Benzene to Hydroquinone Enabled by Engineered Cytochrome P450 Monooxygenase.
Zhou, Hangyu; Wang, Binju; Wang, Fei; Yu, Xiaojuan; Ma, Lixin; Li, Aitao; Reetz, Manfred T.
Affiliation
  • Zhou H; State Key Laboratory of Biocatalysis and Enzyme Engineering, Hubei Collaborative Innovation Center for Green Transformation of Bio-Resources, Hubei Key Laboratory of Industrial Biotechnology, School of Life Sciences, Hubei University, Wuhan, 430062, P. R. China.
  • Wang B; State Key Laboratory of Physical Chemistry of Solid Surfaces and Fujian Provincial Key Laboratory of Theoretical and Computational Chemistry, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, 360015, P. R. China.
  • Wang F; State Key Laboratory of Biocatalysis and Enzyme Engineering, Hubei Collaborative Innovation Center for Green Transformation of Bio-Resources, Hubei Key Laboratory of Industrial Biotechnology, School of Life Sciences, Hubei University, Wuhan, 430062, P. R. China.
  • Yu X; State Key Laboratory of Biocatalysis and Enzyme Engineering, Hubei Collaborative Innovation Center for Green Transformation of Bio-Resources, Hubei Key Laboratory of Industrial Biotechnology, School of Life Sciences, Hubei University, Wuhan, 430062, P. R. China.
  • Ma L; State Key Laboratory of Biocatalysis and Enzyme Engineering, Hubei Collaborative Innovation Center for Green Transformation of Bio-Resources, Hubei Key Laboratory of Industrial Biotechnology, School of Life Sciences, Hubei University, Wuhan, 430062, P. R. China.
  • Li A; State Key Laboratory of Biocatalysis and Enzyme Engineering, Hubei Collaborative Innovation Center for Green Transformation of Bio-Resources, Hubei Key Laboratory of Industrial Biotechnology, School of Life Sciences, Hubei University, Wuhan, 430062, P. R. China.
  • Reetz MT; Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, 32 West 7th Avenue, Tianjin Airport Economic Area, Tianjin, 300308, China.
Angew Chem Int Ed Engl ; 58(3): 764-768, 2019 01 14.
Article in En | MEDLINE | ID: mdl-30511432
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Benzene / Cytochrome P-450 Enzyme System / Hydroquinones Language: En Journal: Angew Chem Int Ed Engl Year: 2019 Document type: Article Country of publication: Germany
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Benzene / Cytochrome P-450 Enzyme System / Hydroquinones Language: En Journal: Angew Chem Int Ed Engl Year: 2019 Document type: Article Country of publication: Germany