Cyclin C directly stimulates Drp1 GTP affinity to mediate stress-induced mitochondrial hyperfission.

Ganesan, Vidyaramanan; Willis, Stephen D; Chang, Kai-Ti; Beluch, Samuel; Cooper, Katrina F; Strich, Randy

Ganesan, Vidyaramanan; Willis, Stephen D; Chang, Kai-Ti; Beluch, Samuel; Cooper, Katrina F; Strich, Randy.

Affiliation

Ganesan V; Department of Molecular Biology, Graduate School of Biomedical Sciences, Rowan University School of Osteopathic Medicine, Stratford, NJ 08084.
Willis SD; Department of Molecular Biology, Graduate School of Biomedical Sciences, Rowan University School of Osteopathic Medicine, Stratford, NJ 08084.
Chang KT; Department of Molecular Biology, Graduate School of Biomedical Sciences, Rowan University School of Osteopathic Medicine, Stratford, NJ 08084.
Beluch S; Department of Molecular Biology, Graduate School of Biomedical Sciences, Rowan University School of Osteopathic Medicine, Stratford, NJ 08084.
Cooper KF; Department of Biological Sciences, Rutgers University, New Brunswick, NJ 08901.
Strich R; Department of Molecular Biology, Graduate School of Biomedical Sciences, Rowan University School of Osteopathic Medicine, Stratford, NJ 08084.

Mol Biol Cell ; 30(3): 302-311, 2019 02 01.

Article in En | MEDLINE | ID: mdl-30516433

Subject(s)

Cyclin C/metabolism; Guanosine Triphosphate/metabolism; Microtubule-Associated Proteins/metabolism; Mitochondria/metabolism; Stress, Physiological; Actin Cytoskeleton/metabolism; Animals; Fibroblasts/metabolism; Humans; Mice; Protein Binding; Protein Domains; Protein Multimerization

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Stress, Physiological / Cyclin C / Guanosine Triphosphate / Microtubule-Associated Proteins / Mitochondria Limits: Animals / Humans Language: En Journal: Mol Biol Cell Journal subject: BIOLOGIA MOLECULAR Year: 2019 Document type: Article Country of publication: United States

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