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Discovery of in Vivo Chemical Probes for Treating Alzheimer's Disease: Dual Phosphodiesterase 5 (PDE5) and Class I Histone Deacetylase Selective Inhibitors.
Rabal, Obdulia; Sánchez-Arias, Juan A; Cuadrado-Tejedor, Mar; de Miguel, Irene; Pérez-González, Marta; García-Barroso, Carolina; Ugarte, Ana; Estella-Hermoso de Mendoza, Ander; Sáez, Elena; Espelosin, Maria; Ursua, Susana; Haizhong, Tan; Wei, Wu; Musheng, Xu; Garcia-Osta, Ana; Oyarzabal, Julen.
Affiliation
  • Cuadrado-Tejedor M; Anatomy Department, School of Medicine , University of Navarra , Irunlarrea 1 , E-31008 Pamplona , Spain.
  • Haizhong T; WuXi Apptec (Tianjin) Co. Ltd. , TEDA, No. 111 HuangHai Road, Fourth Avenue , Tianjin 300456 , PR China.
  • Wei W; WuXi Apptec (Tianjin) Co. Ltd. , TEDA, No. 111 HuangHai Road, Fourth Avenue , Tianjin 300456 , PR China.
  • Musheng X; WuXi Apptec (Tianjin) Co. Ltd. , TEDA, No. 111 HuangHai Road, Fourth Avenue , Tianjin 300456 , PR China.
ACS Chem Neurosci ; 10(3): 1765-1782, 2019 03 20.
Article in En | MEDLINE | ID: mdl-30525452
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cyclic Nucleotide Phosphodiesterases, Type 5 / Histone Deacetylase Inhibitors / Phosphodiesterase 5 Inhibitors / Alzheimer Disease Limits: Animals / Humans Language: En Journal: ACS Chem Neurosci Year: 2019 Document type: Article Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cyclic Nucleotide Phosphodiesterases, Type 5 / Histone Deacetylase Inhibitors / Phosphodiesterase 5 Inhibitors / Alzheimer Disease Limits: Animals / Humans Language: En Journal: ACS Chem Neurosci Year: 2019 Document type: Article Country of publication: United States