[Effect of smoking on chronic rhinosinusitis complicated with lower respiratory tract disease].

Objective: To study the effect of smoking on chronic rhinosinusitis with lower respiratory tract diseases and underlaying mechanism. Method: The data of 54 patients diagnosed as CRS with lower respiratory disease (Group A) and 60 patients with CRS (Group B) from otolaryngology head and neck surgery in Wuhan Central Hospital and Renmin Hospital of Wuhan University from January 2014 to December 2017 were analyzed, retrospectively. According to the history of smoking, all patients were divided into smoking group (Group C) and non-smoking group (Group D). Nasal secretory microbial cultures were performed. Result: Patients with CRS with lower respiratory disease had higher smoking rate than patients with CRS alone(P<0.05). CRS patients with smoking increased the rate of bacterial infection in lower respiratory and increased the incidence of lower respiratory disease in patients with CRS (P<0.05). Conclusion: Smoking is an important risk factor for CRS complicated with lower respiratory disease.