[Clear cell sarcoma or gastrointestinal neuroectodermal tumor (GNET) of the tongue? Case report and review of the literature of an extremely rare tumor localization]. / Sarcome à cellules claires ou tumeur neuroectodermique gastro-intestinale de la langue ? Une observation avec revue de la littérature dans une localisation exceptionnelle.
Ann Pathol
; 39(2): 167-171, 2019 Apr.
Article
in Fr
| MEDLINE
| ID: mdl-30554833
ABSTRACT
Clear cells sarcomas (CCS) are exceptionally rare in the tongue, with, to our knowledge, only three previous reports in anglo-saxon literature. Through our case, we will discuss the differential diagnosis of clear cells tumors of the tongue and bring this tumour closer to the newly described entity of the gastrointestinal tract named "clear cells sarcoma-like gastrointestinal (SCCLGI)", recently renamed "gastrointestinal neuroectodermal tumour (GNET)". SCCLGI/GNET share morphological and molecular characteristics with SCC but had until then been observed only in the digestive tract. Our case could be a lingual localization of a SCCLGI/GNET. SCC and SCCLGI/GNET characteristic molecular profil involves EWSR1-ATF1 [t(12; 22) (q13; q12)] and EWSR1-CREB1 [t(2; 22) (q34; q12)] fusion genes, but it is not specific of these tumours.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Tongue Neoplasms
/
Sarcoma, Clear Cell
/
Neuroectodermal Tumors
Type of study:
Diagnostic_studies
Limits:
Adult
/
Female
/
Humans
Language:
Fr
Journal:
Ann Pathol
Year:
2019
Document type:
Article
Affiliation country:
France