Signatures within the esophageal microbiome are associated with host genetics, age, and disease.

Deshpande, Nandan P; Riordan, Stephen M; Castaño-Rodríguez, Natalia; Wilkins, Marc R; Kaakoush, Nadeem O

Deshpande, Nandan P; Riordan, Stephen M; Castaño-Rodríguez, Natalia; Wilkins, Marc R; Kaakoush, Nadeem O.

Affiliation

Deshpande NP; Systems Biology Initiative, School of Biotechnology and Biomolecular Sciences, UNSW Sydney, Sydney, NSW, 2052, Australia.
Riordan SM; Gastrointestinal and Liver Unit, The Prince of Wales Hospital, Randwick, NSW, 2031, Australia.
Castaño-Rodríguez N; School of Biotechnology and Biomolecular Sciences, UNSW Sydney, Sydney, NSW, 2052, Australia.
Wilkins MR; Systems Biology Initiative, School of Biotechnology and Biomolecular Sciences, UNSW Sydney, Sydney, NSW, 2052, Australia.
Kaakoush NO; School of Biotechnology and Biomolecular Sciences, UNSW Sydney, Sydney, NSW, 2052, Australia.

Microbiome ; 6(1): 227, 2018 12 17.

Article in En | MEDLINE | ID: mdl-30558669

Subject(s)

Adenocarcinoma/etiology; Bacteria/classification; Bacteriophages/classification; Esophageal Neoplasms/etiology; Esophagus/microbiology; Lactic Acid/metabolism; Metagenomics/methods; Polymorphism, Single Nucleotide; Adenocarcinoma/microbiology; Age Factors; Aged; Bacteria/genetics; Bacteria/isolation & purification; Bacteria/metabolism; Bacteriophages/genetics; Bacteriophages/isolation & purification; DNA, Bacterial/genetics; DNA, Ribosomal/genetics; Esophageal Neoplasms/microbiology; Female; High-Throughput Nucleotide Sequencing; Humans; Male; Middle Aged; Nerve Tissue Proteins/genetics; Oncogene Proteins/genetics; Phylogeny; Prevotella/classification; Prevotella/genetics; Prevotella/isolation & purification; Prospective Studies; RNA, Ribosomal, 16S/genetics; RNA, Ribosomal, 18S/genetics; Receptor, Notch2/genetics; Sequence Analysis, DNA; Streptococcus/classification; Streptococcus/genetics; Streptococcus/isolation & purification

Key words

Community types; Esophagus; Metagenomics; Microbiota; Single nucleotide polymorphisms

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bacteria / Bacteriophages / Esophageal Neoplasms / Adenocarcinoma / Lactic Acid / Polymorphism, Single Nucleotide / Esophagus / Metagenomics Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: Microbiome Year: 2018 Document type: Article Affiliation country: Australia

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