A facile approach for the synthesis of nido-carborane fused oxazoles via one pot deboronation/cyclization of 9-amide-o-carboranes.
Chem Commun (Camb)
; 55(6): 830-833, 2019 Jan 15.
Article
in En
| MEDLINE
| ID: mdl-30574956
ABSTRACT
A one pot deboronation/cyclization of 9-amide-o-carboranes for the synthesis of nido-7,8-carborane fused oxazole by cooperation of Pd(OAc)2, AgOAc and K2CO3 has been developed. A plausible mechanism involving an amide directed electrophilic palladation of the B-H bond and deboronation/cyclization process was proposed based on the successful isolation and structural characterization of the key deboronated intermediate.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
Chem Commun (Camb)
Journal subject:
QUIMICA
Year:
2019
Document type:
Article