Effect of melatonin on EGF- and VEGF-induced monolayer permeability of HUVECs.

Yang, Ling; Zhang, Yujie; Ma, Yadong; Du, Jun; Gu, Luo; Zheng, Lu; Zhang, Xiaoying

Yang, Ling; Zhang, Yujie; Ma, Yadong; Du, Jun; Gu, Luo; Zheng, Lu; Zhang, Xiaoying.

Affiliation

Yang L; Department of Cardiology, The Third Affiliated Hospital of Soochow University , Changzhou, Jiangsu , China.
Zhang Y; Department of Physiology, Nanjing Medical University , Nanjing, Jiangsu , China.
Ma Y; Jiangsu Key Lab of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing Medical University , Nanjing, Jiangsu , China.
Du J; Department of Physiology, Nanjing Medical University , Nanjing, Jiangsu , China.
Gu L; Department of Physiology, Nanjing Medical University , Nanjing, Jiangsu , China.
Zheng L; Jiangsu Key Lab of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing Medical University , Nanjing, Jiangsu , China.
Zhang X; Department of Physiology, Nanjing Medical University , Nanjing, Jiangsu , China.

Am J Physiol Heart Circ Physiol ; 316(5): H1178-H1191, 2019 05 01.

Article in En | MEDLINE | ID: mdl-30575440

Subject(s)

Capillary Permeability/drug effects; Epidermal Growth Factor/pharmacology; Human Umbilical Vein Endothelial Cells/drug effects; Melatonin/pharmacology; Vascular Endothelial Growth Factor A/pharmacology; Antigens, CD/metabolism; Cadherins/metabolism; Cells, Cultured; ErbB Receptors/agonists; ErbB Receptors/metabolism; Extracellular Signal-Regulated MAP Kinases/metabolism; Human Umbilical Vein Endothelial Cells/metabolism; Humans; Phosphorylation; Proto-Oncogene Proteins c-akt/metabolism; Signal Transduction; Tyrosine; Vascular Endothelial Growth Factor Receptor-2/agonists; Vascular Endothelial Growth Factor Receptor-2/metabolism

Key words

AKT; epidermal growth factor; growth factors; human umbilical vein endothelial cells; melatonin; permeability; vascular endothelial growth factor; vascular-endothelial cadherin

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Capillary Permeability / Vascular Endothelial Growth Factor A / Epidermal Growth Factor / Human Umbilical Vein Endothelial Cells / Melatonin Limits: Humans Language: En Journal: Am J Physiol Heart Circ Physiol Journal subject: CARDIOLOGIA / FISIOLOGIA Year: 2019 Document type: Article Affiliation country: China Country of publication: United States

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