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Platelet Serotonin Aggravates Myocardial Ischemia/Reperfusion Injury via Neutrophil Degranulation.
Mauler, Maximilian; Herr, Nadine; Schoenichen, Claudia; Witsch, Thilo; Marchini, Timoteo; Härdtner, Carmen; Koentges, Christoph; Kienle, Korbinian; Ollivier, Véronique; Schell, Maximilian; Dorner, Ludwig; Wippel, Christopher; Stallmann, Daniela; Normann, Claus; Bugger, Heiko; Walther, Paul; Wolf, Dennis; Ahrens, Ingo; Lämmermann, Tim; Ho-Tin-Noé, Benoît; Ley, Klaus; Bode, Christoph; Hilgendorf, Ingo; Duerschmied, Daniel.
Affiliation
  • Mauler M; Faculty of Biology (M.M., K.K.), University of Freiburg, Germany.
  • Herr N; Faculty of Medicine (M.M., N.H., C.S., T.W., T.M., C.H., C.K., M.S., L.D., C.W., D.S., C.N., H.B., D.W., C.B., I.H., D.D.), University of Freiburg, Germany.
  • Schoenichen C; Department of Cardiology and Angiology I, Heart Center (M.M., N.H., C.S., T.M., C.H., C.K., M.S., L.D., C.W., D.S., H.B., D.W., I.A., C.B., I.H., D.D.), University of Freiburg, Germany.
  • Witsch T; Faculty of Medicine (M.M., N.H., C.S., T.W., T.M., C.H., C.K., M.S., L.D., C.W., D.S., C.N., H.B., D.W., C.B., I.H., D.D.), University of Freiburg, Germany.
  • Marchini T; Department of Cardiology and Angiology I, Heart Center (M.M., N.H., C.S., T.M., C.H., C.K., M.S., L.D., C.W., D.S., H.B., D.W., I.A., C.B., I.H., D.D.), University of Freiburg, Germany.
  • Härdtner C; Faculty of Medicine (M.M., N.H., C.S., T.W., T.M., C.H., C.K., M.S., L.D., C.W., D.S., C.N., H.B., D.W., C.B., I.H., D.D.), University of Freiburg, Germany.
  • Koentges C; Department of Cardiology and Angiology I, Heart Center (M.M., N.H., C.S., T.M., C.H., C.K., M.S., L.D., C.W., D.S., H.B., D.W., I.A., C.B., I.H., D.D.), University of Freiburg, Germany.
  • Kienle K; Faculty of Medicine (M.M., N.H., C.S., T.W., T.M., C.H., C.K., M.S., L.D., C.W., D.S., C.N., H.B., D.W., C.B., I.H., D.D.), University of Freiburg, Germany.
  • Ollivier V; Faculty of Medicine (M.M., N.H., C.S., T.W., T.M., C.H., C.K., M.S., L.D., C.W., D.S., C.N., H.B., D.W., C.B., I.H., D.D.), University of Freiburg, Germany.
  • Schell M; Department of Cardiology and Angiology I, Heart Center (M.M., N.H., C.S., T.M., C.H., C.K., M.S., L.D., C.W., D.S., H.B., D.W., I.A., C.B., I.H., D.D.), University of Freiburg, Germany.
  • Dorner L; Faculty of Medicine (M.M., N.H., C.S., T.W., T.M., C.H., C.K., M.S., L.D., C.W., D.S., C.N., H.B., D.W., C.B., I.H., D.D.), University of Freiburg, Germany.
  • Wippel C; Department of Cardiology and Angiology I, Heart Center (M.M., N.H., C.S., T.M., C.H., C.K., M.S., L.D., C.W., D.S., H.B., D.W., I.A., C.B., I.H., D.D.), University of Freiburg, Germany.
  • Stallmann D; Faculty of Medicine (M.M., N.H., C.S., T.W., T.M., C.H., C.K., M.S., L.D., C.W., D.S., C.N., H.B., D.W., C.B., I.H., D.D.), University of Freiburg, Germany.
  • Normann C; Department of Cardiology and Angiology I, Heart Center (M.M., N.H., C.S., T.M., C.H., C.K., M.S., L.D., C.W., D.S., H.B., D.W., I.A., C.B., I.H., D.D.), University of Freiburg, Germany.
  • Bugger H; Faculty of Biology (M.M., K.K.), University of Freiburg, Germany.
  • Walther P; Max Planck Institute of Immunobiology and Epigenetics, Group Immune Cell Dynamics (K.K., T.L.), Germany.
  • Wolf D; INSERM Unit 1148, University Paris Diderot (V.O., B.H-T-N.), France.
  • Ahrens I; Laboratory for Vascular Translational Science, Sorbonne Paris Cité (V.O., B.H-T-N.), France.
  • Lämmermann T; Faculty of Medicine (M.M., N.H., C.S., T.W., T.M., C.H., C.K., M.S., L.D., C.W., D.S., C.N., H.B., D.W., C.B., I.H., D.D.), University of Freiburg, Germany.
  • Ho-Tin-Noé B; Department of Cardiology and Angiology I, Heart Center (M.M., N.H., C.S., T.M., C.H., C.K., M.S., L.D., C.W., D.S., H.B., D.W., I.A., C.B., I.H., D.D.), University of Freiburg, Germany.
  • Ley K; Faculty of Medicine (M.M., N.H., C.S., T.W., T.M., C.H., C.K., M.S., L.D., C.W., D.S., C.N., H.B., D.W., C.B., I.H., D.D.), University of Freiburg, Germany.
  • Bode C; Department of Cardiology and Angiology I, Heart Center (M.M., N.H., C.S., T.M., C.H., C.K., M.S., L.D., C.W., D.S., H.B., D.W., I.A., C.B., I.H., D.D.), University of Freiburg, Germany.
  • Hilgendorf I; Faculty of Medicine (M.M., N.H., C.S., T.W., T.M., C.H., C.K., M.S., L.D., C.W., D.S., C.N., H.B., D.W., C.B., I.H., D.D.), University of Freiburg, Germany.
  • Duerschmied D; Department of Cardiology and Angiology I, Heart Center (M.M., N.H., C.S., T.M., C.H., C.K., M.S., L.D., C.W., D.S., H.B., D.W., I.A., C.B., I.H., D.D.), University of Freiburg, Germany.
Circulation ; 139(7): 918-931, 2019 02 12.
Article in En | MEDLINE | ID: mdl-30586717
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Blood Platelets / Myocardial Reperfusion Injury / Serotonin / Cell Degranulation / Myocardial Infarction / Myocardium / Neutrophils Type of study: Observational_studies Limits: Animals / Humans Language: En Journal: Circulation Year: 2019 Document type: Article Affiliation country: Germany Country of publication: United States
Fulltext
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XML
PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Blood Platelets / Myocardial Reperfusion Injury / Serotonin / Cell Degranulation / Myocardial Infarction / Myocardium / Neutrophils Type of study: Observational_studies Limits: Animals / Humans Language: En Journal: Circulation Year: 2019 Document type: Article Affiliation country: Germany Country of publication: United States