[A Case of Suspected Therapy-Related Leukemia after Chemotherapy for Breast Cancer].
Gan To Kagaku Ryoho
; 45(12): 1775-1777, 2018 Dec.
Article
in Ja
| MEDLINE
| ID: mdl-30587740
ABSTRACT
Therapy-related leukemia(TRL)is a distinctive clinical syndrome that occurs after exposure to chemotherapy or radiotherapy. We report a case of suspected TRLafter chemotherapy in a patient with breast cancer. A 61-year-old woman underwent total mastectomy and sentinel lymph node biopsy(negative)for her breast cancer. Histopathologic analysis showed invasive ductal carcinoma, pStage I. Her subtype histology was Luminal B-type, and postoperative adjuvant chemotherapy and endocrine therapy were administered. Four years after chemotherapy, a blood examination showed pancytopenia. Bone marrow examination showed acute promyelocytic leukemia. She was treated with chemotherapy and achieved complete remission. Breast cancer provides long-term survival after treatment. Attention should be paid to the occurrence of TRLin breast cancer surveillance.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Breast Neoplasms
/
Leukemia
/
Antineoplastic Combined Chemotherapy Protocols
/
Carcinoma, Ductal, Breast
Limits:
Female
/
Humans
/
Middle aged
Language:
Ja
Journal:
Gan To Kagaku Ryoho
Year:
2018
Document type:
Article