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Genetic Organization of Open Chromatin Domains Situated in Polytene Chromosome Interbands in Drosophila.
Zykova, T Yu; Popova, O O; Khoroshko, V A; Levitsky, V G; Lavrov, S A; Zhimulev, I F.
Affiliation
  • Zykova TY; Institute of Molecular and Cell Biology, Siberian Branch, Russian Academy of Sciences, Novosibirsk, 630090, Russia. vatolina@mcb.nsc.ru.
  • Popova OO; Institute of Molecular and Cell Biology, Siberian Branch, Russian Academy of Sciences, Novosibirsk, 630090, Russia.
  • Khoroshko VA; Institute of Molecular and Cell Biology, Siberian Branch, Russian Academy of Sciences, Novosibirsk, 630090, Russia.
  • Levitsky VG; Institute of Cytology and Genetics, Siberian Branch, Russian Academy of Sciences, Novosibirsk, 630090, Russia.
  • Lavrov SA; Novosibirsk State University, Novosibirsk, 630090, Russia.
  • Zhimulev IF; Institute of Molecular Genetics, Russian Academy of Sciences, pl. Akademika Kurchatova 46, Moscow, 123182, Russia.
Dokl Biochem Biophys ; 483(1): 297-301, 2018 Nov.
Article in En | MEDLINE | ID: mdl-30607724
ABSTRACT
New data on the organization of genes entirely located in the open domains for chromatin transcription and occupying only one chromosome structure (interband) were obtained. The characteristic features of these genes are the small size (on average, 1-2 kb), depletion of the replicative complex proteins in the regulatory region, and the presence of specific motifs for binding transcription factors, as compared to the genes occupying two structures (interband and gray band). The biological function of these genes is associated primarily with the processes of gene expression and RNA metabolism.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: RNA / Chromatin / Gene Expression Regulation / Drosophila Proteins / DNA-Binding Proteins / Polytene Chromosomes Limits: Animals Language: En Journal: Dokl Biochem Biophys Journal subject: BIOFISICA / BIOQUIMICA Year: 2018 Document type: Article Affiliation country: RUSSIA
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: RNA / Chromatin / Gene Expression Regulation / Drosophila Proteins / DNA-Binding Proteins / Polytene Chromosomes Limits: Animals Language: En Journal: Dokl Biochem Biophys Journal subject: BIOFISICA / BIOQUIMICA Year: 2018 Document type: Article Affiliation country: RUSSIA